Shipping to the U.S. has not yet resumed. We are awaiting final confirmation from Qantas Airways’ legal team that it is safe to uplift parcels to the U.S.

This delay is affecting all international shipments into the U.S. until airlines and postal services receive legal clearance. Unfortunately, this is outside of our control.

Australia Post, who work in partnership with Qantas for international freight, has announced it expects to resume U.S. services by 25 September. On this basis, we remain confident that parcels will be uplifted within September and possibly within the coming days.

Orders can still be placed as usual. Our team will pack your items and dispatch them to our postal agent, where they will be securely held until Qantas resumes services.

We sincerely appreciate your patience, trust, and continued support during this frustrating time.

For any questions or concerns, please don’t hesitate to contact us via email or phone.

Many thanks, the Inhouse Pharmacy Team.

This page is not found

Our most common searches

Here are some helpful links instead

Ooops, sorry the page you requested cannot be found.

Are you looking for:
Spiractin 25 (Spironolactone) Spiractin general information What is Spiractin used for? Spiractin tablets 25mg are used to reduce fluid retention and swelling (oedema) which is caused by several conditions, including congestive heart failure, hypertension (high blood pressure), liver cirrhosis and kidney disease. Spiractin 25 can be used alone to treat hypertension or in combination with other antihypertensive medications like beta blockers, to enhance their activity. Spiractin tablets 25mg is also used to increase blood potassium levels, which occurs in a condition called hypokalaemia (low blood potassium) and to treat hyperaldosteronism, which is caused by excess secretion by the adrenal gland of the hormone aldosterone (involved in regulating sodium and potassium levels), both of which can cause fluid retention. Spiractin 25 has anti-androgen activity which is used in the treatment of female hirsutism (androgen-related increase in facial and body hair) and can be used as an anti-androgen component of transgender hormone therapy, to help stimulate the development of female sexual characteristics for male to female transsexuals. How does Spiractin work? Spiractin tablets 25mg contain spironolactone, a potassium-sparing diuretic (water pill) that acts as an antagonist of the hormone aldosterone, by binding to the aldosterone receptor blocking its action. This action of spironolactone in Spiractin tablets 25mg increases sodium excretion and reduces potassium loss at the distal renal tubule of the kidney. The overall effect of this action is to increase water excretion in the urine which reduces fluid build-up in the tissues, increase blood potassium levels and lower sblood pressure. Spironolactone in Spiractin tablets 25mg also has moderate anti-androgenic activity as it binds to the androgen receptor competing with dihydrotestosterone (DHT) an active metabolite of testosterone. Binding of DHT to the androgen receptor promotes male characteristics therefore, blocking the action of DHT helps reduce male characteristics. Another anti-androgenic action of Spiractin 25 is that it blocks the synthesis of a testosterone by the ovaries. What does Spiractin contain? Spiractin tablets 25mg contain the active ingredient spironolactone, a potassium-sparing diuretic used to treat oedema in various conditions. They also contain quinoline yellow, sunset yellow, erythrosine, polysorbate, peppermint oil, povidone, microcrystalline cellulose, maize starch, sodium starch glycollate, talc, magnesium stearate and lactose. Treating oedema with Spiractin Spiractin tablets 25mg contain spironolactone, a potassium-sparing diuretic (water pill) that is used to treat fluid retention (oedema) caused by several conditions, including congestive heart failure, hypertension (high blood pressure), liver cirrhosis and kidney disease. Spironolactone in Spiractin tablets 25mg works by blocking the action of the hormone aldosterone on the kidneys, which increases excretion of excess water and sodium from the body while at the same time maintaining blood potassium levels. Spiractin for hypertension Spiractin tablets 25mg contain spironolactone, a potassium-sparing diuretic that is used to treat hypertension or high blood pressure, which increases risk of cardiovascular disease and if uncontrolled can cause kidney damage, stroke, heart attack and heart failure. Spironolactone in Spiractin tablets 25mg binds to the receptor for the hormone aldosterone on the kidneys, blocking the action of aldosterone, which increases sodium excretion and reduces potassium loss at the distal renal tubule of the kidney. This action of spironolactone in Spiractin tablets 25mg increases water excretion in the urine which reduces fluid build-up in the tissues, increase blood potassium levels and lowers blood pressure. Spiractin for transgender treatment Spiractin tablets 25mg contain spironolactone, which is primarily used as a diuretic, to reduce fluid retention in conditions such as congestive heart failure, hypertension (high blood pressure), liver cirrhosis and kidney disease. Spironolactone in Spiractin tablets 25mg also acts as an anti-androgen by binding to the androgen receptor and competing with dihydrotestosterone (DHT), the active metabolite of testosterone, which promotes male characteristics, thereby blocking the action of DHT. Using an anti-androgen like spironolactone (usually in high doses of 200–400 mg per day) allows the amount of oestrogen administered for feminising hormone therapy to be reduced while optimising the hormone regime needed to stimulate breast development, feminisation of skin, and female fat distribution. What are the side effects of Spiractin? The most commonly reported side effects when taking Spiractin includes nausea, vomiting, headache, abdominal cramps and pain, diarrhoea, headache, drowsiness, lethargy, hair loss and excessive hair growth. Other side effects include skin rash, menstrual period changes in women, breast enlargement (gynaecomastia) and sexual problems (impotence) in men. When should Spiractin not be used? You should not use Spiractin tablets 25mg if you: are allergic to spironolactone or any ingredients in Spiractin are pregnant or are breastfeeding have kidney or liver disease have high potassium levels in your blood due to a potassium rich diet or if you are taking medications or supplements that increase blood potassium levels are not producing or passing urine are taking other medications that may interact with Spiractin, such as potassium supplements, non-steroidal anti-inflammatory drugs like indomethacin or mefenamic acid, aspirin, digoxin for heart failure, carbenoxolone for mouth ulcers, other diuretics, the ACE inhibitors antihypertensives, ammonium chloride in some cough medications, cholestyramine for lowering blood cholesterol What medications interact with Spiractin? Several medications interact with Spiractin tablets 25mg and should either not be taken while you are taking Spiractin or only after discussion and instruction from your doctor: Drugs that cause a serious reaction with Spiractin: potassium supplements, ammonium chloride in some cough medications, cholestyramine for lowering blood cholesterol, the ACE inhibitors antihypertensives Drugs that affect Spiractin: non-steroidal anti-inflammatory drugs like indomethacin or mefenamic acid and aspirin, carbenoxolone for mouth ulcers Drugs that are affected by Spiractin: digoxin for heart failure How should Spiractin be taken? You should take your Spiractin tablets 25mg with a glass of water with or without food, once or twice daily. The dose you take depends on your condition and what you are being treated for and should be as recommended by your doctor. You should continue taking your Spiractin tablets 25mg even if you are feeling well, which may be for a few days or several weeks and your doctor may increase your dose during treatment. How long should you take Spiractin? You should continue taking your Spiractin tablets 25mg even if you are feeling well, which may be for a few days or several weeks and your doctor may increase your dose during treatment. Missed dose of Spiractin If you miss a dose of Spiractin tablets 25mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Spiractin be stored? You should store your Spiractin tablets 25mg below 30°C in a cool dry place.
Nizonide (Nitazoxanide 500mg) Nizonide general information What is Nizonide used for? Nizonide tablets 500mg are used to treat diarrhoea caused by infection with the parasitic protozoal (single cell) organism Giardia lamblia, causing Giardiasis or Cryptosporidium parvum, causing Cryptosporidiosis. Both organisims live in the intestines and are passed in the faeces and can survive outside the body for long periods of time. Infection is usually from food or water contaminated with faeces and is easily spread by contact and lack of good hygiene. Symptoms of Giardiasis usually develop 9-15 days after infection and can last up to 6 weeks; they include diarrhoea, gas, greasy stools that tend to float, stomach or abdominal cramps, nausea, vomiting and dehydration due to loss of fluids, although in some cases there are no symptoms. Symptoms of cryptosporidiosis usually develop 2-10 after infection and last for 1-2 weeks; they include watery diarrhoea, stomach cramps or pain, dehydration, nausea, vomiting, fever and weight loss. Nizonide tablets 500mg kill the parasite and relieve the symptoms of infection. How does Nizonide work? Nizonide tablets 500mg contain nitazoxanide, a thiazolide class of drug that has broad-spectrum anti-parasitic and antiviral activity, and is used as an antiprotozoal to treat giardiasis and cryptosporidiosis to relieve symptoms and clear up the parasitic infection. Nitazoxanide in Nizonide tablets 500mg and its active metabolite tizoxanide are thought to work by interfering with an enzyme activity (pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction) that promotes conversion of specific chemicals into an energy source needed for survival of the protozoal parasite. This action of nitazoxanide in Nizonide tablets 500mg inhibits growth of the parasite, which kills the parasite and prevents spread of infection, allowing symptoms of infection to clear up for both giardiasis and cryptosporidiosis. Nizonide tablets 500mg are effective for larval as well as adult stages of the lifecycle and are effective within 3 days of treatment. What does Nizonide contain? Nizonide tablets 500mg contain the active ingredient nitazoxanide, an antiprotozoal used to treat giardiasis and cryptosporidiosis to relieve symptoms and clear up the parasitic infection. Treating giardiasis and cryptosporidiosis with Nizonide Nizonide tablets 500mg contain the antiprotozoal nitazoxanide, used to treat diarrhoea caused by infection with the parasitic protozoal (single cell) organism Giardia lamblia, causing Giardiasis or Cryptosporidium parvum, causing Cryptosporidiosis. These parasitic infections are usually due to consuming food or water contaminated with faeces and are easily spread by contact and lack of good hygiene. Symptoms of Giardiasis usually develop 9-15 days after infection and can last up to 6 weeks; they include diarrhoea, gas, greasy stools that tend to float, stomach or abdominal cramps, nausea, vomiting and dehydration due to loss of fluids, although in some cases there are no symptoms. Symptoms of cryptosporidiosis usually develop 2-10 after infection and last for 1-2 weeks; they include watery diarrhoea, stomach cramps or pain, dehydration, nausea, vomiting, fever, weight loss. Nitazoxanide in Nizonide tablets 500mg is are thought to work by interfering with the conversion of specific chemicals into an energy source needed for the parasitic protozoal cell survival. This inhibits growth of the parasite, which kills the parasite and prevents spread of infection, allowing symptoms of infection to clear up for both giardiasis and cryptosporidiosis. What are the side effects of Nizonide? The most commonly reported side effects when taking Nizonide tablets 500mg include, headache, stomach pain, upset stomach, change in colour of urine. When should Nizonide not be used? You should not use Nizonide tablets 500mg if you: are allergic to nitazoxanide or any ingredients in Nizonide are pregnant or are breastfeeding have kidney or liver disease are taking medicines that interact with Nizonide, including warfarin, which increases risk of drug toxicity How should Nizonide be taken? You should take your Nizonide tablets 500mg, swallowed whole with a glass of water and with food twice daily (every 12 hours) for 3 days. Your symptoms should improve within 3 days, if not you should visit your doctor. How long should you take Nizonide? You should take your Nizonide tablets 500mg for 3 days and if your symptoms have not improved you should visit your doctor. Missed dose of Nizonide If you miss a dose of Nizonide tablets 500mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Nizonide be stored? You should store your Nizonide tablets 500mg below 25°C in a cool dry place.
Itrazole 100mg (Itraconazole) Itrazole general information What is Itrazole used for? Itrazole capsules 100mg are used to treat a variety of superficial and systemic fungal infections in various parts of the body. Fungal infections that Itrazole 100 is used for include: Persistent infections of the skin with pityriasis versicolor, which caused by the yeast-like fungus malassezia and characterised by rash and patches of flaky skin on the trunk, neck or arms. Persistent infections with the fungus tinea (also called ringworm) in various parts of the body including the body (tinea corporis), foot (tinea pedis) and groin (tinea cruris or jock itch). Candidiasis (thrush) of the mucus membranes such as in the mouth and vagina, also of the skin. Persistent infections of the vagina with the yeast candida (candidiasis). Infection of the nail (onychomycosis) with yeast or dermatophyte fungi like tinea. Fungal keratitis, an infection of the cornea of the eye by mould fungi like aspergillus or the yeast Candida, resulting in inflammation. Systemic fungal infections that can affect internal organs such as histoplasmosis a rare systemic fungal infection from inhalation of a soil fungus into the lung causing flu-like symptoms; also aspergillosis, a lung infection caused by breathing in spores of the mould fungus aspergillus. These systemic fungal infections are more common in people who are immunocompromised. How does Itrazole work? Itrazole capsules 100mg contain itraconazole broad-spectrum antifungal drug belonging to the triazole group of antifungals. Itraconazole in Itrazole capsules 100mg is a potent and specific inhibitor of fungal enzymes necessary for the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells. A lack of ergosterol weakens the fungal cell membrane, causing the cell contents to leak out, which kills the fungus. This prevents the infection from spreading, relieving symptoms caused by the infection, including, itching and inflammation. What does Itrazole contain? Itrazole capsules 100mg contain the active ingredient itraconazole a broad-spectrum antifungal drug, used to treat and prevent a variety of fungal infections. They also contain sugar spheres, hydroxypropylmethyl cellulose, sorbitan stearate, hydrated silica colloidal, titanium dioxide, red iron oxide and gelatin and opacode S-1-7078 White. Treating fungal infections with with Itrazole Itrazole capsules 100mg contain itraconazole, a broad-spectrum antifungal drug that is used to treat a wide range of superficial and systemic fungal infections, caused by a variety of susceptible fungal species. Itrazole capsules 100mg specifically inhibit the synthesis of ergosterol, an important component of fungal cell membrane, which kills the fungus and stops it spreading; relieving the itching, scaling and other more severe symptoms caused by the fungal infection. Fungal infections that can be treated with Itrazole capsules 100mg include: Persistent infections of the skin with pityriasis versicolor, which caused by the yeast-like fungus malassezia and characterised by rash and patches of flaky skin on the trunk, neck or arms. Persistent infections with the fungus tinea (also called ringworm) in various parts of the body including the body (tinea corporis), foot (tinea pedis) and groin (tinea cruris or jock itch). Candidiasis (thrush) of the mucus membranes such as in the mouth and vagina, also of the skin. Persistent infections of the vagina with the yeast candida (candidiasis). Infection of the nail (onychomycosis) with yeast or dermatophyte fungi like tinea. Fungal keratitis, an infection of the cornea of the eye by mould fungi like aspergillus or the yeast Candida, resulting in inflammation. Systemic fungal infections that can affect internal organs such as histoplasmosis a rare systemic fungal infection from inhalation of a soil fungus into the lung causing flu-like symptoms; also aspergillosis, a lung infection caused by breathing in spores of the mould fungus Aspergillus. These systemic fungal infections are more common in people who are immunocompromised. Itrazole for thrush Itrazole capsules 100mg contain itraconazole, a synthetic broad-spectrum antifungal agent that is used to treat a variety of fungal infections including thrush or candidiasis, which is caused by the yeast candida albicans. Although any site on the body can become infected with candida, including the gastrointestinal tract, the most common site of infection are the mucous membranes of the mouth and vagina, with symptoms including creamy/white lesions or discharge and itching or irritation. Itrazole capsules 100mg specifically inhibit the synthesis of ergosterol, an important component of fungal cell membrane, which kills the fungus and stops it spreading. In this way Itrazole capsules 100mg relieves the symptoms of thrush in all its locations, and prevents constant reinfection in chronic recurrent vaginal thrush. What are the side effects of Itrazole? The most commonly reported side effects when taking Itrazole capsules 100mg include: upset stomach, stomach cramps, nausea and vomiting, diarrhoea, skin rash, headache, constipation, dizziness, menstrual disorders. When should Itrazole not be used? You should not use Itrazole capsules 100mg if you: are allergic to itraconazole or any other azole drug or any ingredients in Itrazole are pregnant or are breastfeeding, without discussion with your doctor have kidney or liver disease are taking medicines that interact with Itrazole, including, the antiviral rifampicin, rifabutin or zidovudine; terfenadine or astemizole for allergy, cisapride for reflux, the anticonvulsant phenytoin, the diuretic hydrochlorothiazide, medicines for diabetes such as glipizide, tolbutamide or glibenclamide, theophylline for asthma, the immunosuppressants tacrolimus and cyclosporine, some benzodiazepines such as midazolam, cholesterol lowering drugs like simvastatin and lovastatin, ergotamine for migraine or ergometrine to prevent bleeding after childbirth, the calcium channel blocker nisoldipine for high blood pressure and angina, the antibiotics clarithromycin and erythromycin, the antipsychotic pimozide What medications interact with Itrazole? Several medications interact with Itrazole and should either not be taken while you are taking Itrazole or only after discussion and instruction from your doctor: Drugs that cause a serious reaction with Itrazole: cisapride for reflux can cause heart problems Drugs that affect Itrazole: the anticonvulsant phenytoin, the antiviral rifampicin, rifabutin or zidovudine; the diuretic hydrochlorothiazide, the antibiotics clarithromycin and erythromycin Drugs that are affected by Itrazole: medicines for diabetes such as glipizide, tolbutamide or glibenclamide; theophylline for asthma, immunosuppressants tacrolimus and cyclosporine, some benzodiazepines such as midazolam, cholesterol lowering drugs like simvastatin and lovastatin, ergot alkaloids like ergotamine for migraine or ergometrine to prevent bleeding after childbirth, the calcium channel blocker nisoldipine for high blood pressure and angina, the antipsychotic pimozide How should Itrazole be taken? You should take your Itrazole capsules 100mg swallowed whole with a glass of water and with food once or twice daily depending on what you are being treated and on your doctor’s recommendations. The dose you take and for how long depends on the type and severity of your infection and your doctor’s recommendations. You should always finish your course of Itrazole capsules 100mg, which may be for a few days or weeks, if not, the infection may not clear up completely. How long should you take Itrazole? You should always finish your course of Itrazole capsules 100mg, which may be for a few days or weeks, if not, the infection may not clear up completely. Missed dose of Itrazole If you miss a dose of Itrazole capsules 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Itrazole be stored? You should store your Itrazole below 25°C in a cool dry place.
Rimadyl 75mg (Carprofen) 60's Rimadyl general information What is Rimadyl used for? Rimadyl chewable tablets 75mg are a medication used for dogs to treat and manage the pain and inflammation that can be caused by osteoarthritis. Many dogs suffer from osteoarthritis, particularly as they age. Osteoarthritis is caused by wear and tear of the joints and can cause pain, swelling and stiffness, particularly in the legs, hips and backbone, which can restrict your dog’s activity and cause lameness. Rimadyl chewable tablets 75mg can help relieve symptoms of osteoarthritis and improve your dog’s mobility. Rimadyl chewables are also used to reduce pain following orthopaedic and soft tissue surgery in dogs. Rimadyl chewable tablets 75mg are intended for use for dogs only and should not be given to cats or other pets. How does Rimadyl work? Rimadyl chewable tablets 75mg contain carprofen a non-steroidal anti-inflammatory drug (NSAID) belonging to the propionic acid class that has anti-inflammatory, analgesic (pain relief) and antipyretic (reduces fever) properties. NSAIDs inhibit the cyclooxygenase (COX) enzyme responsible for the production of chemicals called prostaglandins, which are mediators of a variety of cellular processes as well as inflammation. There are two COX enzymes, COX-1 which is needed for normal cell functions and COX-2 which is involved in the inflammatory process. Carprofen in Rimadyl chewables acts specifically on the inhibition of COX-2 resulting in anti-inflammatory activity which relieves the pain, swelling and stiffness in the joints caused by osteoarthritis. What does Rimadyl contain? Rimadyl chewable tablets 75mg contain the active ingredient carprofen a non-steroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis in dogs. What doses of Rimadyl are available? Rimadyl chewable tablets are available from Inhouse Pharmacy in 3 doses: 25mg chewable tablets in packets of 60 tablets 75mg chewable tablets in packets of 14 tablets 100mg chewable tablets in packets of 60 tablets Treating osteoarthritis in dogs with Rimadyl Rimadyl chewable tablets 75mg contain carprofen a non-steroidal anti-inflammatory drug (NSAID) used to treat dogs to help manage the pain and inflammation caused by osteoarthritis. Many dogs suffer from osteoarthritis, particularly as they age. Osteoarthritis is caused by wear and tear of the joints, particularly in the legs, hips and backbone, which can restrict your dog’s activity and cause lameness. Carprofen in Rimadyl chewables specifically inhibits the COX-2 enzyme responsible for the production of chemicals called prostaglandins, which are mediators of inflammation. The anti-inflammatory activity of Rimadyl chewable tablets 75mg relieves the pain, swelling and stiffness in the joints caused by osteoarthritis. What are the side effects of Rimadyl? The most commonly reported side effects in dogs when given Rimadyl chewable tablets 75mg include: gastrointestinal problems; vomiting, diarrhoea and loss of appetite, lethargy and behavioural changes. If you observe signs of intolerance to chewable Rimadyl tablets 75mg in your dog you should stop giving them Rimadyl chewables and seek help from your vet. When should Rimadyl not be used? You should not give Rimadyl chewable tablets 75mg to your dog if your dog: has a sensitivity reaction to carprofen or any other NSAID or any other ingredients in Rimadyl chewables is younger than 6 months is pregnant or lactating has a heart condition, liver or kidney disease or bleeding disorders has been given other NSAID medication, corticosteroids, some heart drugs (ACE inhibitors) and some drugs for seizure control How should Rimadyl be given to your dog? You should give your dog Rimadyl chewable tablets 75mg by mouth, with or without food and according to your vet’s instructions. The recommended dose is 2mg/lb or 4.4mg/kg of body weight daily, which can be given as a single dose once daily or divided and into two doses given as 1mg/lb or 2.2mg/kg twice daily. Rimadyl chewables will help relieve symptoms of osteoarthritis in your dog and you should see signs of improvement within a few days. However Rimadyl chewable tablets 75mg will not cure your dog’s osteoarthritis, so you should continue to give them to your dog for as long as recommended by your vet. How long should you give Rimadyl to your dog? Rimadyl chewable tablets 75mg will help relieve symptoms of osteoarthritis in your dog and you should see signs of improvement within a few days, Rimadyl chewables will not cure your dog’s osteoarthritis, so you should continue to give them to your dog for as long as recommended by your vet. Missed dose of Rimadyl If you forget to give a dose of Rimadyl chewable tablets 75mg to your dog, administer it as soon as you remember, unless it is time to give the next dose, then skip the missed dose. Do not give your dog a double dose. How should Rimadyl be stored? You should store your dog’s Rimadyl chewable tablets 75mg below 25°C in a cool dry place and protect from light.
Newven (Desvenlafaxine 100mg) Newven general information What is Newven used for? Newven tablets 100mg are used to treat major depression and symptoms of depressive illness, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide. Newven tablets 100mg are also used to treat other mood disorders that affect daily activities and relationships with others including, social anxiety disorder (Social Phobia), panic disorder (panic attacks) and generalised anxiety disorder. Newven tablets 100mg help manage the emotional and physical symptoms of depression to help improve ability to function at work, in family and social life and in leisure activities. How does Newven work? Newven tablets 100mg contain desvenlafaxine which is the active metabolite of venlafaxine, an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) but is structurally and chemically different to other antidepressants. Desvenlafaxine in Newven tablets 100mg acts in the brain to correct the chemical imbalance caused by a lack of certain neurotransmitters (brain chemical that allows nerve cells to communicate) that is thought to be one of the major causes of depression and other mood disorders, particularly a lack of serotonin, which controls many body activities, including regulating mood. Desvenlafaxine is a potent inhibitor of the reuptake of serotonin and noradrenaline, and also weakly inhibits dopamine reuptake, which means that it blocks the re-uptake of serotonin and noradrenaline from the synapse (the gap between nerve cells across which chemical messages are sent from one nerve cell to another). If the re-uptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) is blocked, this means that there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), which allows nerve cells to communicate with each other for longer. The action of Newven tablets 100mg helps relieve symptoms of depression and other mood disorders by increasing the amount of serotonin and noradrenaline in the brain, which in turn increases stimulation of nerve pathways that control mood. Newven tablets 100mg are formulated so that desvenlafaxine is released slowly into the digestive system for extended-release of the medication, to allow for a single dose per day. What does Newven contain? Newven tablets 100mg contain the active ingredient desvenlafaxine, an antidepressant belonging to the Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) that are used to treat depression and other mood disorders. Treating depression with Newven Newven tablets 100mg contain desvenlafaxine which is the active metabolite of venlafaxine, an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs). Newven tablets 100mg are used to treat symptoms of depression, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating and recurrent thoughts of suicide. One of the major causes of depression is thought to be an imbalance of neurotransmitters (brain chemicals that allows nerve cells to communicate), particularly a lack of serotonin that controls mood. Desvenlafaxine in Newven tablets 100mg works by specifically blocking the reuptake of serotonin and noradrenaline from the synapse, or gap between nerve cells across which chemical messages are sent to allow nerve cell to communicate with each other. By preventing the reuptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), so that nerve cells can communicate with each other for longer which increases stimulation of nerve pathways that control mood changes, relieving symptoms of depression. What are the side effects of Newven? The most commonly reported side effects when taking Newven tablets 100mg include: decreased or loss of appetite, dry mouth, diarrhoea, nausea, constipation, sleeplessness, fatigue, drowsiness, increased sweating, vasodilation (hot flashes), hypertension (increase in blood pressure), sexual problems. When should Newven not be used? You should not use Newven tablets 100mg if you: are allergic to desvenlafaxine or any ingredients in Newven are pregnant or are breastfeeding have liver disease have a recent history of myocardial infarction or unstable heart disease are taking any monoamine oxidase inhibitor medications (such as phenelzine and tranylcypromine) as these can cause serious reactions if taken with Newven or within 14 days are taking medicines that interact with Newven monoamine oxidase inhibitors (MAOIs) for depression, other antidepressants, the analgesic tramadol, tryptophan, or phentermine (weight-reducing medicines), sumatriptan for migraine, the antipsychotic pimozide, herbal remedies containing St. John´s Wort, bupropion, for nicotine dependence, the antifungal ketoconazole, the antibiotic erythromycin, clozapine for schizophrenia are taking medication that affects blood clotting as these may increase risk of bleeding if taken with Newven What medications interact with Newven? Several medications interact with Newven tablets 100mg and should either not be taken while you are taking Newven or only after discussion and instruction from your doctor: Drugs that cause a serious reaction with Newven: monoamine oxidase inhibitors (MAOIs) like phenelzine and tranylcypromine for depression, medication that affects blood clotting like warfarin Drugs that affect Newven: the analgesic tramadol, tryptophan, or phentermine (weight-reducing medicines), sumatriptan for migraine, St John's wort, a herbal remedy used to treat mood disorders, cimetidine for reflux and ulcers, antifungal ketoconazole, the antibiotic erythromycin Drugs that are affected by Newven: the antidepressants lithium and Imipramine, clozapine for schizophrenia, the anticoagulant warfarin How should Newven be taken? You should take your Newven tablets 100mg with a glass of water, swallowed whole with or without food You should take your Newven tablets 100mg swallowed whole with a glass of water, with or without food once a day, at the same time each day. Your doctor may increase your dose, depending on what you are being treated for. You should continue take your Newven tablets 100mg for as long as recommended by your doctor, depending on your condition and your doctor’s recommendations, usually for several weeks or months and you should continue your medication even if you feel well. How long should you take Newven? You should continue take your Newven tablets 100mg for as long as recommended by your doctor, depending on your condition and your doctor’s recommendations, usually for several weeks or months and you should continue your medication even if you feel well. Missed dose of Newven If you miss a dose of Newven tablets 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Newven be stored? You should store your Newven tablets 100mg below 25°C in a cool dry place.

Are you looking for:

Spiractin 25 (Spironolactone)

Spiractin general information

What is Spiractin used for?

Spiractin tablets 25mg are used to reduce fluid retention and swelling (oedema) which is caused by several conditions, including congestive heart failure, hypertension (high blood pressure), liver cirrhosis and kidney disease. Spiractin 25 can be used alone to treat hypertension or in combination with other antihypertensive medications like beta blockers, to enhance their activity. Spiractin tablets 25mg is also used to increase blood potassium levels, which occurs in a condition called hypokalaemia (low blood potassium) and to treat hyperaldosteronism, which is caused by excess secretion by the adrenal gland of the hormone aldosterone (involved in regulating sodium and potassium levels), both of which can cause fluid retention. Spiractin 25 has anti-androgen activity which is used in the treatment of female hirsutism (androgen-related increase in facial and body hair) and can be used as an anti-androgen component of transgender hormone therapy, to help stimulate the development of female sexual characteristics for male to female transsexuals.

How does Spiractin work?

Spiractin tablets 25mg contain spironolactone, a potassium-sparing diuretic (water pill) that acts as an antagonist of the hormone aldosterone, by binding to the aldosterone receptor blocking its action. This action of spironolactone in Spiractin tablets 25mg increases sodium excretion and reduces potassium loss at the distal renal tubule of the kidney. The overall effect of this action is to increase water excretion in the urine which reduces fluid build-up in the tissues, increase blood potassium levels and lower sblood pressure. Spironolactone in Spiractin tablets 25mg also has moderate anti-androgenic activity as it binds to the androgen receptor competing with dihydrotestosterone (DHT) an active metabolite of testosterone. Binding of DHT to the androgen receptor promotes male characteristics therefore, blocking the action of DHT helps reduce male characteristics. Another anti-androgenic action of Spiractin 25 is that it blocks the synthesis of a testosterone by the ovaries.

What does Spiractin contain?

Spiractin tablets 25mg contain the active ingredient spironolactone, a potassium-sparing diuretic used to treat oedema in various conditions. They also contain quinoline yellow, sunset yellow, erythrosine, polysorbate, peppermint oil, povidone, microcrystalline cellulose, maize starch, sodium starch glycollate, talc, magnesium stearate and lactose.

Treating oedema with Spiractin

Spiractin tablets 25mg contain spironolactone, a potassium-sparing diuretic (water pill) that is used to treat fluid retention (oedema) caused by several conditions, including congestive heart failure, hypertension (high blood pressure), liver cirrhosis and kidney disease. Spironolactone in Spiractin tablets 25mg works by blocking the action of the hormone aldosterone on the kidneys, which increases excretion of excess water and sodium from the body while at the same time maintaining blood potassium levels.

Spiractin for hypertension

Spiractin tablets 25mg contain spironolactone, a potassium-sparing diuretic that is used to treat hypertension or high blood pressure, which increases risk of cardiovascular disease and if uncontrolled can cause kidney damage, stroke, heart attack and heart failure. Spironolactone in Spiractin tablets 25mg binds to the receptor for the hormone aldosterone on the kidneys, blocking the action of aldosterone, which increases sodium excretion and reduces potassium loss at the distal renal tubule of the kidney. This action of spironolactone in Spiractin tablets 25mg increases water excretion in the urine which reduces fluid build-up in the tissues, increase blood potassium levels and lowers blood pressure.

Spiractin for transgender treatment

Spiractin tablets 25mg contain spironolactone, which is primarily used as a diuretic, to reduce fluid retention in conditions such as congestive heart failure, hypertension (high blood pressure), liver cirrhosis and kidney disease. Spironolactone in Spiractin tablets 25mg also acts as an anti-androgen by binding to the androgen receptor and competing with dihydrotestosterone (DHT), the active metabolite of testosterone, which promotes male characteristics, thereby blocking the action of DHT. Using an anti-androgen like spironolactone (usually in high doses of 200–400 mg per day) allows the amount of oestrogen administered for feminising hormone therapy to be reduced while optimising the hormone regime needed to stimulate breast development, feminisation of skin, and female fat distribution.

What are the side effects of Spiractin?

The most commonly reported side effects when taking Spiractin includes nausea, vomiting, headache, abdominal cramps and pain, diarrhoea, headache, drowsiness, lethargy, hair loss and excessive hair growth. Other side effects include skin rash, menstrual period changes in women, breast enlargement (gynaecomastia) and sexual problems (impotence) in men.

When should Spiractin not be used?

You should not use Spiractin tablets 25mg if you:

are allergic to spironolactone or any ingredients in Spiractin
are pregnant or are breastfeeding
have kidney or liver disease
have high potassium levels in your blood due to a potassium rich diet or if you are taking medications or supplements that increase blood potassium levels
are not producing or passing urine
are taking other medications that may interact with Spiractin, such as potassium supplements, non-steroidal anti-inflammatory drugs like indomethacin or mefenamic acid, aspirin, digoxin for heart failure, carbenoxolone for mouth ulcers, other diuretics, the ACE inhibitors antihypertensives, ammonium chloride in some cough medications, cholestyramine for lowering blood cholesterol

What medications interact with Spiractin?

Several medications interact with Spiractin tablets 25mg and should either not be taken while you are taking Spiractin or only after discussion and instruction from your doctor:

Drugs that cause a serious reaction with Spiractin: potassium supplements, ammonium chloride in some cough medications, cholestyramine for lowering blood cholesterol, the ACE inhibitors antihypertensives
Drugs that affect Spiractin: non-steroidal anti-inflammatory drugs like indomethacin or mefenamic acid and aspirin, carbenoxolone for mouth ulcers
Drugs that are affected by Spiractin: digoxin for heart failure

How should Spiractin be taken?

You should take your Spiractin tablets 25mg with a glass of water with or without food, once or twice daily. The dose you take depends on your condition and what you are being treated for and should be as recommended by your doctor. You should continue taking your Spiractin tablets 25mg even if you are feeling well, which may be for a few days or several weeks and your doctor may increase your dose during treatment.

How long should you take Spiractin?

You should continue taking your Spiractin tablets 25mg even if you are feeling well, which may be for a few days or several weeks and your doctor may increase your dose during treatment.

Missed dose of Spiractin

If you miss a dose of Spiractin tablets 25mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Spiractin be stored?

You should store your Spiractin tablets 25mg below 30°C in a cool dry place.

Nizonide (Nitazoxanide 500mg)

Nizonide general information

What is Nizonide used for?

Nizonide tablets 500mg are used to treat diarrhoea caused by infection with the parasitic protozoal (single cell) organism Giardia lamblia, causing Giardiasis or Cryptosporidium parvum, causing Cryptosporidiosis. Both organisims live in the intestines and are passed in the faeces and can survive outside the body for long periods of time. Infection is usually from food or water contaminated with faeces and is easily spread by contact and lack of good hygiene. Symptoms of Giardiasis usually develop 9-15 days after infection and can last up to 6 weeks; they include diarrhoea, gas, greasy stools that tend to float, stomach or abdominal cramps, nausea, vomiting and dehydration due to loss of fluids, although in some cases there are no symptoms. Symptoms of cryptosporidiosis usually develop 2-10 after infection and last for 1-2 weeks; they include watery diarrhoea, stomach cramps or pain, dehydration, nausea, vomiting, fever and weight loss. Nizonide tablets 500mg kill the parasite and relieve the symptoms of infection.

How does Nizonide work?

Nizonide tablets 500mg contain nitazoxanide, a thiazolide class of drug that has broad-spectrum anti-parasitic and antiviral activity, and is used as an antiprotozoal to treat giardiasis and cryptosporidiosis to relieve symptoms and clear up the parasitic infection. Nitazoxanide in Nizonide tablets 500mg and its active metabolite tizoxanide are thought to work by interfering with an enzyme activity (pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction) that promotes conversion of specific chemicals into an energy source needed for survival of the protozoal parasite. This action of nitazoxanide in Nizonide tablets 500mg inhibits growth of the parasite, which kills the parasite and prevents spread of infection, allowing symptoms of infection to clear up for both giardiasis and cryptosporidiosis. Nizonide tablets 500mg are effective for larval as well as adult stages of the lifecycle and are effective within 3 days of treatment.

What does Nizonide contain?

Nizonide tablets 500mg contain the active ingredient nitazoxanide, an antiprotozoal used to treat giardiasis and cryptosporidiosis to relieve symptoms and clear up the parasitic infection.

Treating giardiasis and cryptosporidiosis with Nizonide

Nizonide tablets 500mg contain the antiprotozoal nitazoxanide, used to treat diarrhoea caused by infection with the parasitic protozoal (single cell) organism Giardia lamblia, causing Giardiasis or Cryptosporidium parvum, causing Cryptosporidiosis. These parasitic infections are usually due to consuming food or water contaminated with faeces and are easily spread by contact and lack of good hygiene. Symptoms of Giardiasis usually develop 9-15 days after infection and can last up to 6 weeks; they include diarrhoea, gas, greasy stools that tend to float, stomach or abdominal cramps, nausea, vomiting and dehydration due to loss of fluids, although in some cases there are no symptoms. Symptoms of cryptosporidiosis usually develop 2-10 after infection and last for 1-2 weeks; they include watery diarrhoea, stomach cramps or pain, dehydration, nausea, vomiting, fever, weight loss. Nitazoxanide in Nizonide tablets 500mg is are thought to work by interfering with the conversion of specific chemicals into an energy source needed for the parasitic protozoal cell survival. This inhibits growth of the parasite, which kills the parasite and prevents spread of infection, allowing symptoms of infection to clear up for both giardiasis and cryptosporidiosis.

What are the side effects of Nizonide?

The most commonly reported side effects when taking Nizonide tablets 500mg include, headache, stomach pain, upset stomach, change in colour of urine.

When should Nizonide not be used?

You should not use Nizonide tablets 500mg if you:

are allergic to nitazoxanide or any ingredients in Nizonide
are pregnant or are breastfeeding
have kidney or liver disease
are taking medicines that interact with Nizonide, including warfarin, which increases risk of drug toxicity

How should Nizonide be taken?

You should take your Nizonide tablets 500mg, swallowed whole with a glass of water and with food twice daily (every 12 hours) for 3 days. Your symptoms should improve within 3 days, if not you should visit your doctor.

How long should you take Nizonide?

You should take your Nizonide tablets 500mg for 3 days and if your symptoms have not improved you should visit your doctor.

Missed dose of Nizonide

If you miss a dose of Nizonide tablets 500mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Nizonide be stored?

You should store your Nizonide tablets 500mg below 25°C in a cool dry place.

Itrazole 100mg (Itraconazole)

Itrazole general information

What is Itrazole used for?

Itrazole capsules 100mg are used to treat a variety of superficial and systemic fungal infections in various parts of the body. Fungal infections that Itrazole 100 is used for include:

Persistent infections of the skin with pityriasis versicolor, which caused by the yeast-like fungus malassezia and characterised by rash and patches of flaky skin on the trunk, neck or arms.
Persistent infections with the fungus tinea (also called ringworm) in various parts of the body including the body (tinea corporis), foot (tinea pedis) and groin (tinea cruris or jock itch).
Candidiasis (thrush) of the mucus membranes such as in the mouth and vagina, also of the skin.
Persistent infections of the vagina with the yeast candida (candidiasis).
Infection of the nail (onychomycosis) with yeast or dermatophyte fungi like tinea.
Fungal keratitis, an infection of the cornea of the eye by mould fungi like aspergillus or the yeast Candida, resulting in inflammation.
Systemic fungal infections that can affect internal organs such as histoplasmosis a rare systemic fungal infection from inhalation of a soil fungus into the lung causing flu-like symptoms; also aspergillosis, a lung infection caused by breathing in spores of the mould fungus aspergillus. These systemic fungal infections are more common in people who are immunocompromised.

How does Itrazole work?

Itrazole capsules 100mg contain itraconazole broad-spectrum antifungal drug belonging to the triazole group of antifungals. Itraconazole in Itrazole capsules 100mg is a potent and specific inhibitor of fungal enzymes necessary for the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells. A lack of ergosterol weakens the fungal cell membrane, causing the cell contents to leak out, which kills the fungus. This prevents the infection from spreading, relieving symptoms caused by the infection, including, itching and inflammation.

What does Itrazole contain?

Itrazole capsules 100mg contain the active ingredient itraconazole a broad-spectrum antifungal drug, used to treat and prevent a variety of fungal infections. They also contain sugar spheres, hydroxypropylmethyl cellulose, sorbitan stearate, hydrated silica colloidal, titanium dioxide, red iron oxide and gelatin and opacode S-1-7078 White.

Treating fungal infections with with Itrazole

Itrazole capsules 100mg contain itraconazole, a broad-spectrum antifungal drug that is used to treat a wide range of superficial and systemic fungal infections, caused by a variety of susceptible fungal species. Itrazole capsules 100mg specifically inhibit the synthesis of ergosterol, an important component of fungal cell membrane, which kills the fungus and stops it spreading; relieving the itching, scaling and other more severe symptoms caused by the fungal infection. Fungal infections that can be treated with Itrazole capsules 100mg include:

Persistent infections of the skin with pityriasis versicolor, which caused by the yeast-like fungus malassezia and characterised by rash and patches of flaky skin on the trunk, neck or arms.
Persistent infections with the fungus tinea (also called ringworm) in various parts of the body including the body (tinea corporis), foot (tinea pedis) and groin (tinea cruris or jock itch).
Candidiasis (thrush) of the mucus membranes such as in the mouth and vagina, also of the skin.
Persistent infections of the vagina with the yeast candida (candidiasis).
Infection of the nail (onychomycosis) with yeast or dermatophyte fungi like tinea.
Fungal keratitis, an infection of the cornea of the eye by mould fungi like aspergillus or the yeast Candida, resulting in inflammation.
Systemic fungal infections that can affect internal organs such as histoplasmosis a rare systemic fungal infection from inhalation of a soil fungus into the lung causing flu-like symptoms; also aspergillosis, a lung infection caused by breathing in spores of the mould fungus Aspergillus. These systemic fungal infections are more common in people who are immunocompromised.

Itrazole for thrush

Itrazole capsules 100mg contain itraconazole, a synthetic broad-spectrum antifungal agent that is used to treat a variety of fungal infections including thrush or candidiasis, which is caused by the yeast candida albicans. Although any site on the body can become infected with candida, including the gastrointestinal tract, the most common site of infection are the mucous membranes of the mouth and vagina, with symptoms including creamy/white lesions or discharge and itching or irritation. Itrazole capsules 100mg specifically inhibit the synthesis of ergosterol, an important component of fungal cell membrane, which kills the fungus and stops it spreading. In this way Itrazole capsules 100mg relieves the symptoms of thrush in all its locations, and prevents constant reinfection in chronic recurrent vaginal thrush.

What are the side effects of Itrazole?

The most commonly reported side effects when taking Itrazole capsules 100mg include: upset stomach, stomach cramps, nausea and vomiting, diarrhoea, skin rash, headache, constipation, dizziness, menstrual disorders.

When should Itrazole not be used?

You should not use Itrazole capsules 100mg if you:

are allergic to itraconazole or any other azole drug or any ingredients in Itrazole
are pregnant or are breastfeeding, without discussion with your doctor
have kidney or liver disease
are taking medicines that interact with Itrazole, including, the antiviral rifampicin, rifabutin or zidovudine; terfenadine or astemizole for allergy, cisapride for reflux, the anticonvulsant phenytoin, the diuretic hydrochlorothiazide, medicines for diabetes such as glipizide, tolbutamide or glibenclamide, theophylline for asthma, the immunosuppressants tacrolimus and cyclosporine, some benzodiazepines such as midazolam, cholesterol lowering drugs like simvastatin and lovastatin, ergotamine for migraine or ergometrine to prevent bleeding after childbirth, the calcium channel blocker nisoldipine for high blood pressure and angina, the antibiotics clarithromycin and erythromycin, the antipsychotic pimozide

What medications interact with Itrazole?

Several medications interact with Itrazole and should either not be taken while you are taking Itrazole or only after discussion and instruction from your doctor:

Drugs that cause a serious reaction with Itrazole: cisapride for reflux can cause heart problems
Drugs that affect Itrazole: the anticonvulsant phenytoin, the antiviral rifampicin, rifabutin or zidovudine; the diuretic hydrochlorothiazide, the antibiotics clarithromycin and erythromycin
Drugs that are affected by Itrazole: medicines for diabetes such as glipizide, tolbutamide or glibenclamide; theophylline for asthma, immunosuppressants tacrolimus and cyclosporine, some benzodiazepines such as midazolam, cholesterol lowering drugs like simvastatin and lovastatin, ergot alkaloids like ergotamine for migraine or ergometrine to prevent bleeding after childbirth, the calcium channel blocker nisoldipine for high blood pressure and angina, the antipsychotic pimozide

How should Itrazole be taken?

You should take your Itrazole capsules 100mg swallowed whole with a glass of water and with food once or twice daily depending on what you are being treated and on your doctor’s recommendations. The dose you take and for how long depends on the type and severity of your infection and your doctor’s recommendations. You should always finish your course of Itrazole capsules 100mg, which may be for a few days or weeks, if not, the infection may not clear up completely.

How long should you take Itrazole?

You should always finish your course of Itrazole capsules 100mg, which may be for a few days or weeks, if not, the infection may not clear up completely.

Missed dose of Itrazole

If you miss a dose of Itrazole capsules 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Itrazole be stored?

You should store your Itrazole below 25°C in a cool dry place.

Rimadyl 75mg (Carprofen) 60's

Rimadyl general information

What is Rimadyl used for?

Rimadyl chewable tablets 75mg are a medication used for dogs to treat and manage the pain and inflammation that can be caused by osteoarthritis. Many dogs suffer from osteoarthritis, particularly as they age. Osteoarthritis is caused by wear and tear of the joints and can cause pain, swelling and stiffness, particularly in the legs, hips and backbone, which can restrict your dog’s activity and cause lameness. Rimadyl chewable tablets 75mg can help relieve symptoms of osteoarthritis and improve your dog’s mobility. Rimadyl chewables are also used to reduce pain following orthopaedic and soft tissue surgery in dogs. Rimadyl chewable tablets 75mg are intended for use for dogs only and should not be given to cats or other pets.

How does Rimadyl work?

Rimadyl chewable tablets 75mg contain carprofen a non-steroidal anti-inflammatory drug (NSAID) belonging to the propionic acid class that has anti-inflammatory, analgesic (pain relief) and antipyretic (reduces fever) properties. NSAIDs inhibit the cyclooxygenase (COX) enzyme responsible for the production of chemicals called prostaglandins, which are mediators of a variety of cellular processes as well as inflammation. There are two COX enzymes, COX-1 which is needed for normal cell functions and COX-2 which is involved in the inflammatory process. Carprofen in Rimadyl chewables acts specifically on the inhibition of COX-2 resulting in anti-inflammatory activity which relieves the pain, swelling and stiffness in the joints caused by osteoarthritis.

What does Rimadyl contain?

Rimadyl chewable tablets 75mg contain the active ingredient carprofen a non-steroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis in dogs.

What doses of Rimadyl are available?

Rimadyl chewable tablets are available from Inhouse Pharmacy in 3 doses:

25mg chewable tablets in packets of 60 tablets
75mg chewable tablets in packets of 14 tablets
100mg chewable tablets in packets of 60 tablets

Treating osteoarthritis in dogs with Rimadyl

Rimadyl chewable tablets 75mg contain carprofen a non-steroidal anti-inflammatory drug (NSAID) used to treat dogs to help manage the pain and inflammation caused by osteoarthritis. Many dogs suffer from osteoarthritis, particularly as they age. Osteoarthritis is caused by wear and tear of the joints, particularly in the legs, hips and backbone, which can restrict your dog’s activity and cause lameness. Carprofen in Rimadyl chewables specifically inhibits the COX-2 enzyme responsible for the production of chemicals called prostaglandins, which are mediators of inflammation. The anti-inflammatory activity of Rimadyl chewable tablets 75mg relieves the pain, swelling and stiffness in the joints caused by osteoarthritis.

What are the side effects of Rimadyl?

The most commonly reported side effects in dogs when given Rimadyl chewable tablets 75mg include: gastrointestinal problems; vomiting, diarrhoea and loss of appetite, lethargy and behavioural changes. If you observe signs of intolerance to chewable Rimadyl tablets 75mg in your dog you should stop giving them Rimadyl chewables and seek help from your vet.

When should Rimadyl not be used?

You should not give Rimadyl chewable tablets 75mg to your dog if your dog:

has a sensitivity reaction to carprofen or any other NSAID or any other ingredients in Rimadyl chewables
is younger than 6 months
is pregnant or lactating
has a heart condition, liver or kidney disease or bleeding disorders
has been given other NSAID medication, corticosteroids, some heart drugs (ACE inhibitors) and some drugs for seizure control

How should Rimadyl be given to your dog?

You should give your dog Rimadyl chewable tablets 75mg by mouth, with or without food and according to your vet’s instructions. The recommended dose is 2mg/lb or 4.4mg/kg of body weight daily, which can be given as a single dose once daily or divided and into two doses given as 1mg/lb or 2.2mg/kg twice daily. Rimadyl chewables will help relieve symptoms of osteoarthritis in your dog and you should see signs of improvement within a few days. However Rimadyl chewable tablets 75mg will not cure your dog’s osteoarthritis, so you should continue to give them to your dog for as long as recommended by your vet.

How long should you give Rimadyl to your dog?

Rimadyl chewable tablets 75mg will help relieve symptoms of osteoarthritis in your dog and you should see signs of improvement within a few days, Rimadyl chewables will not cure your dog’s osteoarthritis, so you should continue to give them to your dog for as long as recommended by your vet.

Missed dose of Rimadyl

If you forget to give a dose of Rimadyl chewable tablets 75mg to your dog, administer it as soon as you remember, unless it is time to give the next dose, then skip the missed dose. Do not give your dog a double dose.

How should Rimadyl be stored?

You should store your dog’s Rimadyl chewable tablets 75mg below 25°C in a cool dry place and protect from light.

Newven (Desvenlafaxine 100mg)

Newven general information

What is Newven used for?

Newven tablets 100mg are used to treat major depression and symptoms of depressive illness, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide. Newven tablets 100mg are also used to treat other mood disorders that affect daily activities and relationships with others including, social anxiety disorder (Social Phobia), panic disorder (panic attacks) and generalised anxiety disorder. Newven tablets 100mg help manage the emotional and physical symptoms of depression to help improve ability to function at work, in family and social life and in leisure activities.

How does Newven work?

Newven tablets 100mg contain desvenlafaxine which is the active metabolite of venlafaxine, an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) but is structurally and chemically different to other antidepressants. Desvenlafaxine in Newven tablets 100mg acts in the brain to correct the chemical imbalance caused by a lack of certain neurotransmitters (brain chemical that allows nerve cells to communicate) that is thought to be one of the major causes of depression and other mood disorders, particularly a lack of serotonin, which controls many body activities, including regulating mood. Desvenlafaxine is a potent inhibitor of the reuptake of serotonin and noradrenaline, and also weakly inhibits dopamine reuptake, which means that it blocks the re-uptake of serotonin and noradrenaline from the synapse (the gap between nerve cells across which chemical messages are sent from one nerve cell to another). If the re-uptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) is blocked, this means that there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), which allows nerve cells to communicate with each other for longer. The action of Newven tablets 100mg helps relieve symptoms of depression and other mood disorders by increasing the amount of serotonin and noradrenaline in the brain, which in turn increases stimulation of nerve pathways that control mood. Newven tablets 100mg are formulated so that desvenlafaxine is released slowly into the digestive system for extended-release of the medication, to allow for a single dose per day.

What does Newven contain?

Newven tablets 100mg contain the active ingredient desvenlafaxine, an antidepressant belonging to the Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) that are used to treat depression and other mood disorders.

Treating depression with Newven

Newven tablets 100mg contain desvenlafaxine which is the active metabolite of venlafaxine, an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs). Newven tablets 100mg are used to treat symptoms of depression, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating and recurrent thoughts of suicide. One of the major causes of depression is thought to be an imbalance of neurotransmitters (brain chemicals that allows nerve cells to communicate), particularly a lack of serotonin that controls mood. Desvenlafaxine in Newven tablets 100mg works by specifically blocking the reuptake of serotonin and noradrenaline from the synapse, or gap between nerve cells across which chemical messages are sent to allow nerve cell to communicate with each other. By preventing the reuptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), so that nerve cells can communicate with each other for longer which increases stimulation of nerve pathways that control mood changes, relieving symptoms of depression.

What are the side effects of Newven?

The most commonly reported side effects when taking Newven tablets 100mg include: decreased or loss of appetite, dry mouth, diarrhoea, nausea, constipation, sleeplessness, fatigue, drowsiness, increased sweating, vasodilation (hot flashes), hypertension (increase in blood pressure), sexual problems.

When should Newven not be used?

You should not use Newven tablets 100mg if you:

are allergic to desvenlafaxine or any ingredients in Newven
are pregnant or are breastfeeding
have liver disease
have a recent history of myocardial infarction or unstable heart disease
are taking any monoamine oxidase inhibitor medications (such as phenelzine and tranylcypromine) as these can cause serious reactions if taken with Newven or within 14 days
are taking medicines that interact with Newven monoamine oxidase inhibitors (MAOIs) for depression, other antidepressants, the analgesic tramadol, tryptophan, or phentermine (weight-reducing medicines), sumatriptan for migraine, the antipsychotic pimozide, herbal remedies containing St. John´s Wort, bupropion, for nicotine dependence, the antifungal ketoconazole, the antibiotic erythromycin, clozapine for schizophrenia
are taking medication that affects blood clotting as these may increase risk of bleeding if taken with Newven

What medications interact with Newven?

Several medications interact with Newven tablets 100mg and should either not be taken while you are taking Newven or only after discussion and instruction from your doctor:

Drugs that cause a serious reaction with Newven: monoamine oxidase inhibitors (MAOIs) like phenelzine and tranylcypromine for depression, medication that affects blood clotting like warfarin
Drugs that affect Newven: the analgesic tramadol, tryptophan, or phentermine (weight-reducing medicines), sumatriptan for migraine, St John's wort, a herbal remedy used to treat mood disorders, cimetidine for reflux and ulcers, antifungal ketoconazole, the antibiotic erythromycin
Drugs that are affected by Newven: the antidepressants lithium and Imipramine, clozapine for schizophrenia, the anticoagulant warfarin

How should Newven be taken?

You should take your Newven tablets 100mg with a glass of water, swallowed whole with or without food You should take your Newven tablets 100mg swallowed whole with a glass of water, with or without food once a day, at the same time each day. Your doctor may increase your dose, depending on what you are being treated for. You should continue take your Newven tablets 100mg for as long as recommended by your doctor, depending on your condition and your doctor’s recommendations, usually for several weeks or months and you should continue your medication even if you feel well.

How long should you take Newven?

You should continue take your Newven tablets 100mg for as long as recommended by your doctor, depending on your condition and your doctor’s recommendations, usually for several weeks or months and you should continue your medication even if you feel well.

Missed dose of Newven

If you miss a dose of Newven tablets 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Newven be stored?

You should store your Newven tablets 100mg below 25°C in a cool dry place.

TEST2

Shipping delays due to Covid-19 Virus