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Enlafax XR (Venlafaxine 75mg) Enlafax general information What is Enlafax used for? Enlafax XR capsules 75mg (also known as Efexor) are used to treat major depression and symptoms of depressive illness, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide. Enlafax XR capsules 75mg are also used to treat other mood disorders that affect daily activities and relationships with others including, social anxiety disorder (Social Phobia), panic disorder (panic attacks) and generalised anxiety disorder. Enlafax XR capsules 75mg help manage the emotional and physical symptoms of depression and other mood disorders to help improve ability to function at work, in family, social life and in leisure activities. How does Enlafax work? Enlafax XR capsules 75mg contain venlafaxine which is an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) but is structurally and chemically different to other antidepressants. Venlafaxine in Enlafax XR capsules 75mg acts in the brain to correct the chemical imbalance caused by a lack of certain neurotransmitters (brain chemical that allows nerve cells to communicate) that is thought to be one of the major causes of depression and other mood disorders, particularly a lack of serotonin, which controls many body activities, including regulating mood. Venlafaxine is a potent inhibitor of the reuptake of serotonin and noradrenaline, and also weakly inhibits dopamine reuptake, which means that it blocks the re-uptake of serotonin and noradrenaline from the synapse (the gap between nerve cells across which chemical messages are sent from one nerve cell to another). If the re-uptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) is blocked, this means that there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), which allows nerve cells to communicate with each other for longer. The action of Enlafax XR capsules 75mg helps relieve symptoms of depression and other mood disorders by increasing the amount of serotonin and noradrenaline in the brain, which in turn increases stimulation of nerve pathways that control mood. Enlafax XR capsules 75mg are formulated so that venlafaxine is released slowly from tablets within the capsule into the digestive system for extended-release of the drug. What does Enlafax contain? Enlafax XR capsules 75mg contain the active ingredient venlafaxine hydrochloride, an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) used to treat depression and other mood disorders. They also contain hypromellose, Eudragit RS 100, Eudragit E12.5, sodium lauryl sulfate, magnesium stearate, titanium dioxide (E171), gelatin, black ink, iron oxide red (E172). Treating depression with Enlafax Enlafax XR capsules 75mg (also known as Effexor XR in the US) contain venlafaxine which is an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs), used to treat symptoms of depression, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating and recurrent thoughts of suicide. One of the major causes of depression is thought to be an imbalance of neurotransmitters (brain chemicals that allows nerve cells to communicate), particularly a lack of serotonin that controls mood. Enlafax XR capsules 75mg works by specifically blocking the reuptake of serotonin and noradrenaline from the synapse, or gap between nerve cells across which chemical messages are sent to allow nerve cell to communicate with each other. By preventing the reuptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), so that nerve cells can communicate with each other for longer which increases stimulation of nerve pathways that control mood changes, relieving symptoms of depression. Enlafax for anxiety Enlafax XR capsules 75mg contain venlafaxine which is an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs), used to treat several anxiety-related conditions, including social anxiety disorder (Social Phobia), panic disorder (panic attacks) and generalised anxiety disorder, where excessive anxiety causes constant and uncontrollable feelings of worry and distress, feeling irritable, and difficulty thinking and sleeping. Other common symptoms associated with anxiety may include muscle tension, dry mouth, a lump in the throat, cold clammy hands, diarrhoea and nausea. One of the major causes of anxiety is thought to be an imbalance of neurotransmitters (brain chemicals that allows nerve cells to communicate), particularly a lack of serotonin that controls mood and noradrenaline that is related to drive and motivation. If there is a lack of serotonin, the brain cells involved in nerve pathways that control mood changes generate feelings of anxiety and panic instead of well-being, which is associated with high levels of serotonin. Enlafax XR capsules 75mg works by specifically blocking the reuptake of serotonin and noradrenaline from the synapse, or gap between nerve cells across which chemical messages are sent to allow nerve cell to communicate with each other. By preventing the reuptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), so that nerve cells can communicate with each other for longer which increases stimulation of nerve pathways that control mood changes, relieving symptoms of anxiety. What are the side effects of Enlafax? The most commonly reported side effects when taking Enlafax XR capsules 75mg are generally mild and transient and usually disappear with continued treatment. They include: decreased or loss of appetite, dry mouth, diarrhoea, nausea, sleeplessness, fatigue, drowsiness, increased sweating, vasodilation (hot flashes), hypertension (increase in blood pressure), sexual problems. When should Enlafax not be used? You should not use Enlafax XR capsules 75mg if you: are allergic to venlafaxine or any ingredients in Enlafax are pregnant or are breastfeeding have liver or kidney disease, without discussion with your doctor have a recent history of myocardial infarction or unstable heart disease taking any monoamine oxidase inhibitor medications (such as phenelzine and tranylcypromine) as these can cause serious reactions if taken with Enlafax XR or within 14 days are taking medication that affects blood clotting like warfarin as these may increase risk of bleeding if taken with Enlafax are taking medicines that interact with Enlafax including, monoamine oxidase inhibitors (MAOIs) for depression, other antidepressants like lithium and Imipramine, the analgesic tramadol, tryptophan, or phentermine (weight-reducing medicines), migraine medicines like sumatriptan, the antipsychotic pimozide, herbal remedies containing St. John´s Wort, bupropion, for nicotine dependence, the antifungal ketoconazole, the antibiotic erythromycin, clozapine for schizophrenia What medications interact with Enlafax? Several medications interact with Enlafax capsules 75mg and should either not be taken while you are taking Enlafax or only after discussion and instruction from your doctor: Drugs that cause a serious reaction with Enlafax: monoamine oxidase inhibitors (MAOIs) for depression, medication that affects blood clotting like warfarin, as these may increase risk of bleeding if taken with Enlafax Drugs that affect Enlafax: the analgesic tramadol, sibutramine (weight-reducing medicines), medicines used to treat migraine like sumatriptan, St John's wort, a herbal remedy used to treat mood disorders, cimetidine for reflux and ulcers, antifungals like ketoconazole, antibiotics like erythromycin Drugs that are affected by Enlafax: antidepressants like lithium and Imipramine, clozapine for schizophrenia, the anticoagulant warfarin How should Enlafax be taken? You should take your Enlafax XR capsules 75mg with a glass of water, swallowed whole with food once a day, at the same time each day, for several weeks or months, depending on your condition and your doctor’s recommendations. Your doctor may increase your dose, depending on what you are being treated for. You should continue to take your Enlafax XR capsules 75mg regularly for as long as recommended by your doctor, usually for several weeks or months and you should continue your medication even if you feel well. How long should you take Enlafax? You should continue to take your Enlafax XR capsules 75mg regularly for as long as recommended by your doctor, usually for several weeks or months and you should continue your medication even if you feel well. Missed dose of Enlafax If you miss a dose of Enlafax XR capsules 75mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Enlafax be stored? You should store your Enlafax XR capsules 75mg below 25°C in a cool dry place.
Nifuran (Nitrofurantoin 50mg) Nifuran general information What is Nifuran used for? Nifuran tablets 50mg are used to treat acute urinary tract infection and prevent recurrent urinary tract infections that are caused by susceptible bacteria. The most common urinary infection in women is bladder infection or cystitis, and in men infection of the prostate or prostatitis. Nifuran tablets 50mg are also used to treat pyelitis, which is when the infection has travelled up the urinary tract and reached the kidney, causing pain and inflammation. Nifuran tablets 50mg are a specific treatment for urinary tract infections but are not used for other types of bacterial infection. . How does Nifuran work? Nifuran tablets 50mg contain nitrofurantoin, a broad-spectrum antibiotic that is used specifically to treat urinary tract infection caused by a variety of susceptible bacteria. Nitrofurantoin in Nifuran tablets 50mg exerts its antibacterial effect by damaging the bacterial DNA which inhibits bacterial replication and prevents the spread of infection. Riboflavins in the bacterial cell convert nitrofurantoin to a form that is very reactive with bacterial proteins and other macromolecules like DNA, which prevent DNA synthesis as well as other metabolic processes, like production of the bacterial cell wall. This action of nitrofurantoin in Nifuran tablets 50mg kills the bacteria and prevents spread of infection. Nifuran tablets 50mg are effective against most of the bacteria that cause urinary tract infections including, Escherichia coli, Enterococcus Faecalis and several species of Klebsiella, Enterobacter, Staphylococcus and Citrobacter. What does Nifuran contain? Nifuran tablets 50mg contain the active ingredient nitrofurantoin, an antibiotic that is used specifically to treat urinary tract infection. They also contain acacia, alginic acid, lactose monohydrate, magnesium stearate, maize starch, sodium laurilsulfate, sucrose. Treating urinary tract infection with Nifuran Nifuran tablets 50mg contain nitrofurantoin, a broad-spectrum antibiotic that is used to treat acute urinary tract infection and prevent recurrent urinary tract infections that are caused by susceptible bacteria. The most common urinary infection in women is bladder infection or cystitis, and in men infection of the prostate or prostatitis. Nitrofurantoin in Nifuran tablets 50mg is converted by bacterial riboflavins to a form that is very reactive with bacterial proteins and other macromolecules like DNA, which prevent DNA synthesis as well as other metabolic processes like production of the bacterial cell wall. This antibacterial action of nitrofurantoin in Nifuran tablets 50mg inhibits bacterial replication and prevents the spread of infection. What are the side effects of Nifuran? The most commonly reported side effects when taking Nifuran tablets 50mg include gastrointestinal upset, mainly nausea and flatulence, headache, urine discolouration. Less common side effects include, peripheral neuropathy, dizziness; drowsiness. When should Nifuran not be used? You should not use Nifuran tablets 50mg if you: are allergic to nitrofurantoin or any ingredients in Nifuran are pregnant or are breastfeeding have kidney disease or urine problems, such as producing less urine than normal (oliguria) or having trouble producing any urine (anuria) are taking medicines that interact with Nifuran including antacids containing magnesium trisilicate, probenecid and sulphinpyrazone for gout, quinolone antibiotics What medications interact with Nifuran? Several medications interact with Nifuran tablets 50mg and should either not be taken while you are taking Nifuran or only after discussion and instruction from your doctor: Drugs that cause a serious reaction or increase side effects with Nifuran: probenecid and sulphinpyrazone for gout Drugs that affect Nifuran: antacids containing magnesium trisilicate, probenecid and sulphinpyrazone for gout, quinolone How should Nifuran be taken? You should take your Nifuran tablets 50mg swallowed whole with a glass of water and with food or with a glass of milk, 4 times daily for 7 days, if you have an acute urinary tract infection. For prophylaxis (prevention) of urinary tract infection, you should take one tablet at bedtime for up to 6 months. You should continue to take your Nifuran tablets 50mg according to your doctor’s recommendations or until you have completed your course. If you do not complete your course of Nifuran tablets 50mg your infection may not fully clear up or may return. How long should you take Nifuran? You should take your Nifuran tablets 50mg for 7 days for an acute urinary tract infection or for up to 6 months for prophylaxis (prevention) of urinary tract infection. You should complete your course of Nifuran tablets 50mg or your infection may not fully clear up or may return. Missed dose of Nifuran If you miss a dose of Nifuran tablets 50mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Nifuran be stored? You should store your Nifuran tablets 50mg below 25°C in a cool dry place.
Newven (Desvenlafaxine 100mg) Newven general information What is Newven used for? Newven tablets 100mg are used to treat major depression and symptoms of depressive illness, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide. Newven tablets 100mg are also used to treat other mood disorders that affect daily activities and relationships with others including, social anxiety disorder (Social Phobia), panic disorder (panic attacks) and generalised anxiety disorder. Newven tablets 100mg help manage the emotional and physical symptoms of depression to help improve ability to function at work, in family and social life and in leisure activities. How does Newven work? Newven tablets 100mg contain desvenlafaxine which is the active metabolite of venlafaxine, an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) but is structurally and chemically different to other antidepressants. Desvenlafaxine in Newven tablets 100mg acts in the brain to correct the chemical imbalance caused by a lack of certain neurotransmitters (brain chemical that allows nerve cells to communicate) that is thought to be one of the major causes of depression and other mood disorders, particularly a lack of serotonin, which controls many body activities, including regulating mood. Desvenlafaxine is a potent inhibitor of the reuptake of serotonin and noradrenaline, and also weakly inhibits dopamine reuptake, which means that it blocks the re-uptake of serotonin and noradrenaline from the synapse (the gap between nerve cells across which chemical messages are sent from one nerve cell to another). If the re-uptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) is blocked, this means that there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), which allows nerve cells to communicate with each other for longer. The action of Newven tablets 100mg helps relieve symptoms of depression and other mood disorders by increasing the amount of serotonin and noradrenaline in the brain, which in turn increases stimulation of nerve pathways that control mood. Newven tablets 100mg are formulated so that desvenlafaxine is released slowly into the digestive system for extended-release of the medication, to allow for a single dose per day. What does Newven contain? Newven tablets 100mg contain the active ingredient desvenlafaxine, an antidepressant belonging to the Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) that are used to treat depression and other mood disorders. Treating depression with Newven Newven tablets 100mg contain desvenlafaxine which is the active metabolite of venlafaxine, an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs). Newven tablets 100mg are used to treat symptoms of depression, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating and recurrent thoughts of suicide. One of the major causes of depression is thought to be an imbalance of neurotransmitters (brain chemicals that allows nerve cells to communicate), particularly a lack of serotonin that controls mood. Desvenlafaxine in Newven tablets 100mg works by specifically blocking the reuptake of serotonin and noradrenaline from the synapse, or gap between nerve cells across which chemical messages are sent to allow nerve cell to communicate with each other. By preventing the reuptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), so that nerve cells can communicate with each other for longer which increases stimulation of nerve pathways that control mood changes, relieving symptoms of depression. What are the side effects of Newven? The most commonly reported side effects when taking Newven tablets 100mg include: decreased or loss of appetite, dry mouth, diarrhoea, nausea, constipation, sleeplessness, fatigue, drowsiness, increased sweating, vasodilation (hot flashes), hypertension (increase in blood pressure), sexual problems. When should Newven not be used? You should not use Newven tablets 100mg if you: are allergic to desvenlafaxine or any ingredients in Newven are pregnant or are breastfeeding have liver disease have a recent history of myocardial infarction or unstable heart disease are taking any monoamine oxidase inhibitor medications (such as phenelzine and tranylcypromine) as these can cause serious reactions if taken with Newven or within 14 days are taking medicines that interact with Newven monoamine oxidase inhibitors (MAOIs) for depression, other antidepressants, the analgesic tramadol, tryptophan, or phentermine (weight-reducing medicines), sumatriptan for migraine, the antipsychotic pimozide, herbal remedies containing St. John´s Wort, bupropion, for nicotine dependence, the antifungal ketoconazole, the antibiotic erythromycin, clozapine for schizophrenia are taking medication that affects blood clotting as these may increase risk of bleeding if taken with Newven What medications interact with Newven? Several medications interact with Newven tablets 100mg and should either not be taken while you are taking Newven or only after discussion and instruction from your doctor: Drugs that cause a serious reaction with Newven: monoamine oxidase inhibitors (MAOIs) like phenelzine and tranylcypromine for depression, medication that affects blood clotting like warfarin Drugs that affect Newven: the analgesic tramadol, tryptophan, or phentermine (weight-reducing medicines), sumatriptan for migraine, St John's wort, a herbal remedy used to treat mood disorders, cimetidine for reflux and ulcers, antifungal ketoconazole, the antibiotic erythromycin Drugs that are affected by Newven: the antidepressants lithium and Imipramine, clozapine for schizophrenia, the anticoagulant warfarin How should Newven be taken? You should take your Newven tablets 100mg with a glass of water, swallowed whole with or without food You should take your Newven tablets 100mg swallowed whole with a glass of water, with or without food once a day, at the same time each day. Your doctor may increase your dose, depending on what you are being treated for. You should continue take your Newven tablets 100mg for as long as recommended by your doctor, depending on your condition and your doctor’s recommendations, usually for several weeks or months and you should continue your medication even if you feel well. How long should you take Newven? You should continue take your Newven tablets 100mg for as long as recommended by your doctor, depending on your condition and your doctor’s recommendations, usually for several weeks or months and you should continue your medication even if you feel well. Missed dose of Newven If you miss a dose of Newven tablets 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Newven be stored? You should store your Newven tablets 100mg below 25°C in a cool dry place.
Muply (Mupirocin 2%) Ointment Muply general information What is Muply used for? Muply ointment is a topical treatment for a variety of primary bacterial skin infections, including, impetigo, a superficial skin infection most common in young children; folliculitis, infection of the hair root ; furunculosis, also known as boils; ecthyma, a deep, ulcerating infection of the skin caused by streptococcus bacteria. Muply ointment is also used to treat secondary infections that occur in damaged skin, for example due to eczema, psoriasis, atopic dermatitis, herpes (cold sores), epidermolysis bullosa (an inherited diseases characterised by blistering lesions on the skin and mucous membranes), icthyosis (genetic skin disorders that cause dry, fragile skin); also for treatment of infected traumatic lesions such as wounds, ulcers, minor burns, cuts, grazes and insect bites, as well as to prevent the development of infection and help wound healing. How does Muply work? Muply ointment contains mupirocin, an antibiotic that has very potent bactericidal activity, and is used as a topical treatment for a variety of primary skin infections; and secondary infections that occur in damaged skin and in skin lesions. Mupirocin in Muply ointment inhibits protein and RNA synthesis in susceptible bacteria, which include staphylococci, streptococci, and Haemophilus influenza. This action of mupirocin in Muply ointment blocks growth and replication of the susceptible bacteria, and prevents the spread of the infection. What does Muply contain? Muply ointment contains the active ingredient mupirocin 2%, a topical antibiotic used to treat variety of skin infections. Treating skin infections with Muply Muply ointment contains mupirocin, an antibiotic that is used as a topical treatment for a variety of skin infections. Skin infections that Muply ointment is used for include impetigo, a superficial skin infection most common in young children; folliculitis, infection of the hair root; furunculosis, also known as boils; ecthyma, a deep, ulcerating infection of the skin caused by streptococcus bacteria. Muply ointment is also effective against secondary infections that occur in damaged skin due to eczema, psoriasis, atopic dermatitis, herpes and genetic skin disorders that cause dry, fragile skin; as well as for infected traumatic lesions such as wounds, ulcers, minor burns, cuts, grazes and insect bites; and to prevent the development of infection and help wound healing. Mupirocin in Muply ointment inhibits the protein and RNA synthesis in susceptible bacteria, which blocks growth and replication of these bacteria and prevents the spread of the infection. What are the side effects of Muply? The most commonly reported side effects when taking Muply include itching, dryness, burning, redness, stinging, pain or swelling. When should Muply not be used? You should not use Muply ointment if you: are allergic to mupirocin or any ingredients in Muply have an eye or nose infection, as Muply ointment is suitable only for skin infections How should Muply be used? You should apply your Muply ointment to the affected area three times each day. Squeeze a small amount onto your finger tip and rub in gently; always wash your hands before and after applying the ointment and avoid contact with the eyes. Your doctor may recommend applying a gauze to the infected area over the ointment. You should continue to apply your Muply ointment for as long as recommended by your doctor, usually for up to 10 days. How long should you use Muply? You should continue to apply your Muply ointment for as long as recommended by your doctor, usually for up to 10 days. Missed dose of Muply If you miss a dose of Muply ointment apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose. Do not apply a double dose. How should Muply be stored? You should store your Muply ointment below 25°C in a cool dry place; do not freeze the ointment.
Nizonide (Nitazoxanide 500mg) Nizonide general information What is Nizonide used for? Nizonide tablets 500mg are used to treat diarrhoea caused by infection with the parasitic protozoal (single cell) organism Giardia lamblia, causing Giardiasis or Cryptosporidium parvum, causing Cryptosporidiosis. Both organisims live in the intestines and are passed in the faeces and can survive outside the body for long periods of time. Infection is usually from food or water contaminated with faeces and is easily spread by contact and lack of good hygiene. Symptoms of Giardiasis usually develop 9-15 days after infection and can last up to 6 weeks; they include diarrhoea, gas, greasy stools that tend to float, stomach or abdominal cramps, nausea, vomiting and dehydration due to loss of fluids, although in some cases there are no symptoms. Symptoms of cryptosporidiosis usually develop 2-10 after infection and last for 1-2 weeks; they include watery diarrhoea, stomach cramps or pain, dehydration, nausea, vomiting, fever and weight loss. Nizonide tablets 500mg kill the parasite and relieve the symptoms of infection. How does Nizonide work? Nizonide tablets 500mg contain nitazoxanide, a thiazolide class of drug that has broad-spectrum anti-parasitic and antiviral activity, and is used as an antiprotozoal to treat giardiasis and cryptosporidiosis to relieve symptoms and clear up the parasitic infection. Nitazoxanide in Nizonide tablets 500mg and its active metabolite tizoxanide are thought to work by interfering with an enzyme activity (pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction) that promotes conversion of specific chemicals into an energy source needed for survival of the protozoal parasite. This action of nitazoxanide in Nizonide tablets 500mg inhibits growth of the parasite, which kills the parasite and prevents spread of infection, allowing symptoms of infection to clear up for both giardiasis and cryptosporidiosis. Nizonide tablets 500mg are effective for larval as well as adult stages of the lifecycle and are effective within 3 days of treatment. What does Nizonide contain? Nizonide tablets 500mg contain the active ingredient nitazoxanide, an antiprotozoal used to treat giardiasis and cryptosporidiosis to relieve symptoms and clear up the parasitic infection. Treating giardiasis and cryptosporidiosis with Nizonide Nizonide tablets 500mg contain the antiprotozoal nitazoxanide, used to treat diarrhoea caused by infection with the parasitic protozoal (single cell) organism Giardia lamblia, causing Giardiasis or Cryptosporidium parvum, causing Cryptosporidiosis. These parasitic infections are usually due to consuming food or water contaminated with faeces and are easily spread by contact and lack of good hygiene. Symptoms of Giardiasis usually develop 9-15 days after infection and can last up to 6 weeks; they include diarrhoea, gas, greasy stools that tend to float, stomach or abdominal cramps, nausea, vomiting and dehydration due to loss of fluids, although in some cases there are no symptoms. Symptoms of cryptosporidiosis usually develop 2-10 after infection and last for 1-2 weeks; they include watery diarrhoea, stomach cramps or pain, dehydration, nausea, vomiting, fever, weight loss. Nitazoxanide in Nizonide tablets 500mg is are thought to work by interfering with the conversion of specific chemicals into an energy source needed for the parasitic protozoal cell survival. This inhibits growth of the parasite, which kills the parasite and prevents spread of infection, allowing symptoms of infection to clear up for both giardiasis and cryptosporidiosis. What are the side effects of Nizonide? The most commonly reported side effects when taking Nizonide tablets 500mg include, headache, stomach pain, upset stomach, change in colour of urine. When should Nizonide not be used? You should not use Nizonide tablets 500mg if you: are allergic to nitazoxanide or any ingredients in Nizonide are pregnant or are breastfeeding have kidney or liver disease are taking medicines that interact with Nizonide, including warfarin, which increases risk of drug toxicity How should Nizonide be taken? You should take your Nizonide tablets 500mg, swallowed whole with a glass of water and with food twice daily (every 12 hours) for 3 days. Your symptoms should improve within 3 days, if not you should visit your doctor. How long should you take Nizonide? You should take your Nizonide tablets 500mg for 3 days and if your symptoms have not improved you should visit your doctor. Missed dose of Nizonide If you miss a dose of Nizonide tablets 500mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Nizonide be stored? You should store your Nizonide tablets 500mg below 25°C in a cool dry place.

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Enlafax general information

What is Enlafax used for?

Enlafax XR capsules 75mg (also known as Efexor) are used to treat major depression and symptoms of depressive illness, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide. Enlafax XR capsules 75mg are also used to treat other mood disorders that affect daily activities and relationships with others including, social anxiety disorder (Social Phobia), panic disorder (panic attacks) and generalised anxiety disorder. Enlafax XR capsules 75mg help manage the emotional and physical symptoms of depression and other mood disorders to help improve ability to function at work, in family, social life and in leisure activities.

How does Enlafax work?

Enlafax XR capsules 75mg contain venlafaxine which is an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) but is structurally and chemically different to other antidepressants. Venlafaxine in Enlafax XR capsules 75mg acts in the brain to correct the chemical imbalance caused by a lack of certain neurotransmitters (brain chemical that allows nerve cells to communicate) that is thought to be one of the major causes of depression and other mood disorders, particularly a lack of serotonin, which controls many body activities, including regulating mood. Venlafaxine is a potent inhibitor of the reuptake of serotonin and noradrenaline, and also weakly inhibits dopamine reuptake, which means that it blocks the re-uptake of serotonin and noradrenaline from the synapse (the gap between nerve cells across which chemical messages are sent from one nerve cell to another). If the re-uptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) is blocked, this means that there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), which allows nerve cells to communicate with each other for longer. The action of Enlafax XR capsules 75mg helps relieve symptoms of depression and other mood disorders by increasing the amount of serotonin and noradrenaline in the brain, which in turn increases stimulation of nerve pathways that control mood. Enlafax XR capsules 75mg are formulated so that venlafaxine is released slowly from tablets within the capsule into the digestive system for extended-release of the drug.

What does Enlafax contain?

Enlafax XR capsules 75mg contain the active ingredient venlafaxine hydrochloride, an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) used to treat depression and other mood disorders. They also contain hypromellose, Eudragit RS 100, Eudragit E12.5, sodium lauryl sulfate, magnesium stearate, titanium dioxide (E171), gelatin, black ink, iron oxide red (E172).

Treating depression with Enlafax

Enlafax XR capsules 75mg (also known as Effexor XR in the US) contain venlafaxine which is an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs), used to treat symptoms of depression, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating and recurrent thoughts of suicide. One of the major causes of depression is thought to be an imbalance of neurotransmitters (brain chemicals that allows nerve cells to communicate), particularly a lack of serotonin that controls mood. Enlafax XR capsules 75mg works by specifically blocking the reuptake of serotonin and noradrenaline from the synapse, or gap between nerve cells across which chemical messages are sent to allow nerve cell to communicate with each other. By preventing the reuptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), so that nerve cells can communicate with each other for longer which increases stimulation of nerve pathways that control mood changes, relieving symptoms of depression.

Enlafax for anxiety

Enlafax XR capsules 75mg contain venlafaxine which is an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs), used to treat several anxiety-related conditions, including social anxiety disorder (Social Phobia), panic disorder (panic attacks) and generalised anxiety disorder, where excessive anxiety causes constant and uncontrollable feelings of worry and distress, feeling irritable, and difficulty thinking and sleeping. Other common symptoms associated with anxiety may include muscle tension, dry mouth, a lump in the throat, cold clammy hands, diarrhoea and nausea. One of the major causes of anxiety is thought to be an imbalance of neurotransmitters (brain chemicals that allows nerve cells to communicate), particularly a lack of serotonin that controls mood and noradrenaline that is related to drive and motivation. If there is a lack of serotonin, the brain cells involved in nerve pathways that control mood changes generate feelings of anxiety and panic instead of well-being, which is associated with high levels of serotonin. Enlafax XR capsules 75mg works by specifically blocking the reuptake of serotonin and noradrenaline from the synapse, or gap between nerve cells across which chemical messages are sent to allow nerve cell to communicate with each other. By preventing the reuptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), so that nerve cells can communicate with each other for longer which increases stimulation of nerve pathways that control mood changes, relieving symptoms of anxiety.

What are the side effects of Enlafax?

The most commonly reported side effects when taking Enlafax XR capsules 75mg are generally mild and transient and usually disappear with continued treatment. They include: decreased or loss of appetite, dry mouth, diarrhoea, nausea, sleeplessness, fatigue, drowsiness, increased sweating, vasodilation (hot flashes), hypertension (increase in blood pressure), sexual problems.

When should Enlafax not be used?

You should not use Enlafax XR capsules 75mg if you:

are allergic to venlafaxine or any ingredients in Enlafax
are pregnant or are breastfeeding
have liver or kidney disease, without discussion with your doctor
have a recent history of myocardial infarction or unstable heart disease
taking any monoamine oxidase inhibitor medications (such as phenelzine and tranylcypromine) as these can cause serious reactions if taken with Enlafax XR or within 14 days
are taking medication that affects blood clotting like warfarin as these may increase risk of bleeding if taken with Enlafax
are taking medicines that interact with Enlafax including, monoamine oxidase inhibitors (MAOIs) for depression, other antidepressants like lithium and Imipramine, the analgesic tramadol, tryptophan, or phentermine (weight-reducing medicines), migraine medicines like sumatriptan, the antipsychotic pimozide, herbal remedies containing St. John´s Wort, bupropion, for nicotine dependence, the antifungal ketoconazole, the antibiotic erythromycin, clozapine for schizophrenia

What medications interact with Enlafax?

Several medications interact with Enlafax capsules 75mg and should either not be taken while you are taking Enlafax or only after discussion and instruction from your doctor:

Drugs that cause a serious reaction with Enlafax: monoamine oxidase inhibitors (MAOIs) for depression, medication that affects blood clotting like warfarin, as these may increase risk of bleeding if taken with Enlafax
Drugs that affect Enlafax: the analgesic tramadol, sibutramine (weight-reducing medicines), medicines used to treat migraine like sumatriptan, St John's wort, a herbal remedy used to treat mood disorders, cimetidine for reflux and ulcers, antifungals like ketoconazole, antibiotics like erythromycin
Drugs that are affected by Enlafax: antidepressants like lithium and Imipramine, clozapine for schizophrenia, the anticoagulant warfarin

How should Enlafax be taken?

You should take your Enlafax XR capsules 75mg with a glass of water, swallowed whole with food once a day, at the same time each day, for several weeks or months, depending on your condition and your doctor’s recommendations. Your doctor may increase your dose, depending on what you are being treated for. You should continue to take your Enlafax XR capsules 75mg regularly for as long as recommended by your doctor, usually for several weeks or months and you should continue your medication even if you feel well.

How long should you take Enlafax?

You should continue to take your Enlafax XR capsules 75mg regularly for as long as recommended by your doctor, usually for several weeks or months and you should continue your medication even if you feel well.

Missed dose of Enlafax

If you miss a dose of Enlafax XR capsules 75mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Enlafax be stored?

You should store your Enlafax XR capsules 75mg below 25°C in a cool dry place.

Nifuran (Nitrofurantoin 50mg)

Nifuran general information

What is Nifuran used for?

Nifuran tablets 50mg are used to treat acute urinary tract infection and prevent recurrent urinary tract infections that are caused by susceptible bacteria. The most common urinary infection in women is bladder infection or cystitis, and in men infection of the prostate or prostatitis. Nifuran tablets 50mg are also used to treat pyelitis, which is when the infection has travelled up the urinary tract and reached the kidney, causing pain and inflammation. Nifuran tablets 50mg are a specific treatment for urinary tract infections but are not used for other types of bacterial infection. .

How does Nifuran work?

Nifuran tablets 50mg contain nitrofurantoin, a broad-spectrum antibiotic that is used specifically to treat urinary tract infection caused by a variety of susceptible bacteria. Nitrofurantoin in Nifuran tablets 50mg exerts its antibacterial effect by damaging the bacterial DNA which inhibits bacterial replication and prevents the spread of infection. Riboflavins in the bacterial cell convert nitrofurantoin to a form that is very reactive with bacterial proteins and other macromolecules like DNA, which prevent DNA synthesis as well as other metabolic processes, like production of the bacterial cell wall. This action of nitrofurantoin in Nifuran tablets 50mg kills the bacteria and prevents spread of infection. Nifuran tablets 50mg are effective against most of the bacteria that cause urinary tract infections including, Escherichia coli, Enterococcus Faecalis and several species of Klebsiella, Enterobacter, Staphylococcus and Citrobacter.

What does Nifuran contain?

Nifuran tablets 50mg contain the active ingredient nitrofurantoin, an antibiotic that is used specifically to treat urinary tract infection. They also contain acacia, alginic acid, lactose monohydrate, magnesium stearate, maize starch, sodium laurilsulfate, sucrose.

Treating urinary tract infection with Nifuran

Nifuran tablets 50mg contain nitrofurantoin, a broad-spectrum antibiotic that is used to treat acute urinary tract infection and prevent recurrent urinary tract infections that are caused by susceptible bacteria. The most common urinary infection in women is bladder infection or cystitis, and in men infection of the prostate or prostatitis. Nitrofurantoin in Nifuran tablets 50mg is converted by bacterial riboflavins to a form that is very reactive with bacterial proteins and other macromolecules like DNA, which prevent DNA synthesis as well as other metabolic processes like production of the bacterial cell wall. This antibacterial action of nitrofurantoin in Nifuran tablets 50mg inhibits bacterial replication and prevents the spread of infection.

What are the side effects of Nifuran?

The most commonly reported side effects when taking Nifuran tablets 50mg include gastrointestinal upset, mainly nausea and flatulence, headache, urine discolouration. Less common side effects include, peripheral neuropathy, dizziness; drowsiness.

When should Nifuran not be used?

You should not use Nifuran tablets 50mg if you:

are allergic to nitrofurantoin or any ingredients in Nifuran
are pregnant or are breastfeeding
have kidney disease or urine problems, such as producing less urine than normal (oliguria) or having trouble producing any urine (anuria)
are taking medicines that interact with Nifuran including antacids containing magnesium trisilicate, probenecid and sulphinpyrazone for gout, quinolone antibiotics

What medications interact with Nifuran?

Several medications interact with Nifuran tablets 50mg and should either not be taken while you are taking Nifuran or only after discussion and instruction from your doctor:

Drugs that cause a serious reaction or increase side effects with Nifuran: probenecid and sulphinpyrazone for gout
Drugs that affect Nifuran: antacids containing magnesium trisilicate, probenecid and sulphinpyrazone for gout, quinolone

How should Nifuran be taken?

You should take your Nifuran tablets 50mg swallowed whole with a glass of water and with food or with a glass of milk, 4 times daily for 7 days, if you have an acute urinary tract infection. For prophylaxis (prevention) of urinary tract infection, you should take one tablet at bedtime for up to 6 months. You should continue to take your Nifuran tablets 50mg according to your doctor’s recommendations or until you have completed your course. If you do not complete your course of Nifuran tablets 50mg your infection may not fully clear up or may return.

How long should you take Nifuran?

You should take your Nifuran tablets 50mg for 7 days for an acute urinary tract infection or for up to 6 months for prophylaxis (prevention) of urinary tract infection. You should complete your course of Nifuran tablets 50mg or your infection may not fully clear up or may return.

Missed dose of Nifuran

If you miss a dose of Nifuran tablets 50mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Nifuran be stored?

You should store your Nifuran tablets 50mg below 25°C in a cool dry place.

Newven (Desvenlafaxine 100mg)

Newven general information

What is Newven used for?

Newven tablets 100mg are used to treat major depression and symptoms of depressive illness, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide. Newven tablets 100mg are also used to treat other mood disorders that affect daily activities and relationships with others including, social anxiety disorder (Social Phobia), panic disorder (panic attacks) and generalised anxiety disorder. Newven tablets 100mg help manage the emotional and physical symptoms of depression to help improve ability to function at work, in family and social life and in leisure activities.

How does Newven work?

Newven tablets 100mg contain desvenlafaxine which is the active metabolite of venlafaxine, an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) but is structurally and chemically different to other antidepressants. Desvenlafaxine in Newven tablets 100mg acts in the brain to correct the chemical imbalance caused by a lack of certain neurotransmitters (brain chemical that allows nerve cells to communicate) that is thought to be one of the major causes of depression and other mood disorders, particularly a lack of serotonin, which controls many body activities, including regulating mood. Desvenlafaxine is a potent inhibitor of the reuptake of serotonin and noradrenaline, and also weakly inhibits dopamine reuptake, which means that it blocks the re-uptake of serotonin and noradrenaline from the synapse (the gap between nerve cells across which chemical messages are sent from one nerve cell to another). If the re-uptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) is blocked, this means that there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), which allows nerve cells to communicate with each other for longer. The action of Newven tablets 100mg helps relieve symptoms of depression and other mood disorders by increasing the amount of serotonin and noradrenaline in the brain, which in turn increases stimulation of nerve pathways that control mood. Newven tablets 100mg are formulated so that desvenlafaxine is released slowly into the digestive system for extended-release of the medication, to allow for a single dose per day.

What does Newven contain?

Newven tablets 100mg contain the active ingredient desvenlafaxine, an antidepressant belonging to the Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs) that are used to treat depression and other mood disorders.

Treating depression with Newven

Newven tablets 100mg contain desvenlafaxine which is the active metabolite of venlafaxine, an antidepressant belonging to the class of drugs known as Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs). Newven tablets 100mg are used to treat symptoms of depression, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating and recurrent thoughts of suicide. One of the major causes of depression is thought to be an imbalance of neurotransmitters (brain chemicals that allows nerve cells to communicate), particularly a lack of serotonin that controls mood. Desvenlafaxine in Newven tablets 100mg works by specifically blocking the reuptake of serotonin and noradrenaline from the synapse, or gap between nerve cells across which chemical messages are sent to allow nerve cell to communicate with each other. By preventing the reuptake of serotonin and noradrenaline by the first nerve cell (pre-synaptic) there is more neurotransmitter remaining for the receiving nerve cell (post-synaptic), so that nerve cells can communicate with each other for longer which increases stimulation of nerve pathways that control mood changes, relieving symptoms of depression.

What are the side effects of Newven?

The most commonly reported side effects when taking Newven tablets 100mg include: decreased or loss of appetite, dry mouth, diarrhoea, nausea, constipation, sleeplessness, fatigue, drowsiness, increased sweating, vasodilation (hot flashes), hypertension (increase in blood pressure), sexual problems.

When should Newven not be used?

You should not use Newven tablets 100mg if you:

are allergic to desvenlafaxine or any ingredients in Newven
are pregnant or are breastfeeding
have liver disease
have a recent history of myocardial infarction or unstable heart disease
are taking any monoamine oxidase inhibitor medications (such as phenelzine and tranylcypromine) as these can cause serious reactions if taken with Newven or within 14 days
are taking medicines that interact with Newven monoamine oxidase inhibitors (MAOIs) for depression, other antidepressants, the analgesic tramadol, tryptophan, or phentermine (weight-reducing medicines), sumatriptan for migraine, the antipsychotic pimozide, herbal remedies containing St. John´s Wort, bupropion, for nicotine dependence, the antifungal ketoconazole, the antibiotic erythromycin, clozapine for schizophrenia
are taking medication that affects blood clotting as these may increase risk of bleeding if taken with Newven

What medications interact with Newven?

Several medications interact with Newven tablets 100mg and should either not be taken while you are taking Newven or only after discussion and instruction from your doctor:

Drugs that cause a serious reaction with Newven: monoamine oxidase inhibitors (MAOIs) like phenelzine and tranylcypromine for depression, medication that affects blood clotting like warfarin
Drugs that affect Newven: the analgesic tramadol, tryptophan, or phentermine (weight-reducing medicines), sumatriptan for migraine, St John's wort, a herbal remedy used to treat mood disorders, cimetidine for reflux and ulcers, antifungal ketoconazole, the antibiotic erythromycin
Drugs that are affected by Newven: the antidepressants lithium and Imipramine, clozapine for schizophrenia, the anticoagulant warfarin

How should Newven be taken?

You should take your Newven tablets 100mg with a glass of water, swallowed whole with or without food You should take your Newven tablets 100mg swallowed whole with a glass of water, with or without food once a day, at the same time each day. Your doctor may increase your dose, depending on what you are being treated for. You should continue take your Newven tablets 100mg for as long as recommended by your doctor, depending on your condition and your doctor’s recommendations, usually for several weeks or months and you should continue your medication even if you feel well.

How long should you take Newven?

You should continue take your Newven tablets 100mg for as long as recommended by your doctor, depending on your condition and your doctor’s recommendations, usually for several weeks or months and you should continue your medication even if you feel well.

Missed dose of Newven

If you miss a dose of Newven tablets 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Newven be stored?

You should store your Newven tablets 100mg below 25°C in a cool dry place.

Muply (Mupirocin 2%) Ointment

Muply general information

What is Muply used for?

Muply ointment is a topical treatment for a variety of primary bacterial skin infections, including, impetigo, a superficial skin infection most common in young children; folliculitis, infection of the hair root ; furunculosis, also known as boils; ecthyma, a deep, ulcerating infection of the skin caused by streptococcus bacteria. Muply ointment is also used to treat secondary infections that occur in damaged skin, for example due to eczema, psoriasis, atopic dermatitis, herpes (cold sores), epidermolysis bullosa (an inherited diseases characterised by blistering lesions on the skin and mucous membranes), icthyosis (genetic skin disorders that cause dry, fragile skin); also for treatment of infected traumatic lesions such as wounds, ulcers, minor burns, cuts, grazes and insect bites, as well as to prevent the development of infection and help wound healing.

How does Muply work?

Muply ointment contains mupirocin, an antibiotic that has very potent bactericidal activity, and is used as a topical treatment for a variety of primary skin infections; and secondary infections that occur in damaged skin and in skin lesions. Mupirocin in Muply ointment inhibits protein and RNA synthesis in susceptible bacteria, which include staphylococci, streptococci, and Haemophilus influenza. This action of mupirocin in Muply ointment blocks growth and replication of the susceptible bacteria, and prevents the spread of the infection.

What does Muply contain?

Muply ointment contains the active ingredient mupirocin 2%, a topical antibiotic used to treat variety of skin infections.

Treating skin infections with Muply

Muply ointment contains mupirocin, an antibiotic that is used as a topical treatment for a variety of skin infections. Skin infections that Muply ointment is used for include impetigo, a superficial skin infection most common in young children; folliculitis, infection of the hair root; furunculosis, also known as boils; ecthyma, a deep, ulcerating infection of the skin caused by streptococcus bacteria. Muply ointment is also effective against secondary infections that occur in damaged skin due to eczema, psoriasis, atopic dermatitis, herpes and genetic skin disorders that cause dry, fragile skin; as well as for infected traumatic lesions such as wounds, ulcers, minor burns, cuts, grazes and insect bites; and to prevent the development of infection and help wound healing. Mupirocin in Muply ointment inhibits the protein and RNA synthesis in susceptible bacteria, which blocks growth and replication of these bacteria and prevents the spread of the infection.

What are the side effects of Muply?

The most commonly reported side effects when taking Muply include itching, dryness, burning, redness, stinging, pain or swelling.

When should Muply not be used?

You should not use Muply ointment if you:

are allergic to mupirocin or any ingredients in Muply
have an eye or nose infection, as Muply ointment is suitable only for skin infections

How should Muply be used?

You should apply your Muply ointment to the affected area three times each day. Squeeze a small amount onto your finger tip and rub in gently; always wash your hands before and after applying the ointment and avoid contact with the eyes. Your doctor may recommend applying a gauze to the infected area over the ointment. You should continue to apply your Muply ointment for as long as recommended by your doctor, usually for up to 10 days.

How long should you use Muply?

You should continue to apply your Muply ointment for as long as recommended by your doctor, usually for up to 10 days.

Missed dose of Muply

If you miss a dose of Muply ointment apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose. Do not apply a double dose.

How should Muply be stored?

You should store your Muply ointment below 25°C in a cool dry place; do not freeze the ointment.

Nizonide (Nitazoxanide 500mg)

Nizonide general information

What is Nizonide used for?

Nizonide tablets 500mg are used to treat diarrhoea caused by infection with the parasitic protozoal (single cell) organism Giardia lamblia, causing Giardiasis or Cryptosporidium parvum, causing Cryptosporidiosis. Both organisims live in the intestines and are passed in the faeces and can survive outside the body for long periods of time. Infection is usually from food or water contaminated with faeces and is easily spread by contact and lack of good hygiene. Symptoms of Giardiasis usually develop 9-15 days after infection and can last up to 6 weeks; they include diarrhoea, gas, greasy stools that tend to float, stomach or abdominal cramps, nausea, vomiting and dehydration due to loss of fluids, although in some cases there are no symptoms. Symptoms of cryptosporidiosis usually develop 2-10 after infection and last for 1-2 weeks; they include watery diarrhoea, stomach cramps or pain, dehydration, nausea, vomiting, fever and weight loss. Nizonide tablets 500mg kill the parasite and relieve the symptoms of infection.

How does Nizonide work?

Nizonide tablets 500mg contain nitazoxanide, a thiazolide class of drug that has broad-spectrum anti-parasitic and antiviral activity, and is used as an antiprotozoal to treat giardiasis and cryptosporidiosis to relieve symptoms and clear up the parasitic infection. Nitazoxanide in Nizonide tablets 500mg and its active metabolite tizoxanide are thought to work by interfering with an enzyme activity (pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction) that promotes conversion of specific chemicals into an energy source needed for survival of the protozoal parasite. This action of nitazoxanide in Nizonide tablets 500mg inhibits growth of the parasite, which kills the parasite and prevents spread of infection, allowing symptoms of infection to clear up for both giardiasis and cryptosporidiosis. Nizonide tablets 500mg are effective for larval as well as adult stages of the lifecycle and are effective within 3 days of treatment.

What does Nizonide contain?

Nizonide tablets 500mg contain the active ingredient nitazoxanide, an antiprotozoal used to treat giardiasis and cryptosporidiosis to relieve symptoms and clear up the parasitic infection.

Treating giardiasis and cryptosporidiosis with Nizonide

Nizonide tablets 500mg contain the antiprotozoal nitazoxanide, used to treat diarrhoea caused by infection with the parasitic protozoal (single cell) organism Giardia lamblia, causing Giardiasis or Cryptosporidium parvum, causing Cryptosporidiosis. These parasitic infections are usually due to consuming food or water contaminated with faeces and are easily spread by contact and lack of good hygiene. Symptoms of Giardiasis usually develop 9-15 days after infection and can last up to 6 weeks; they include diarrhoea, gas, greasy stools that tend to float, stomach or abdominal cramps, nausea, vomiting and dehydration due to loss of fluids, although in some cases there are no symptoms. Symptoms of cryptosporidiosis usually develop 2-10 after infection and last for 1-2 weeks; they include watery diarrhoea, stomach cramps or pain, dehydration, nausea, vomiting, fever, weight loss. Nitazoxanide in Nizonide tablets 500mg is are thought to work by interfering with the conversion of specific chemicals into an energy source needed for the parasitic protozoal cell survival. This inhibits growth of the parasite, which kills the parasite and prevents spread of infection, allowing symptoms of infection to clear up for both giardiasis and cryptosporidiosis.

What are the side effects of Nizonide?

The most commonly reported side effects when taking Nizonide tablets 500mg include, headache, stomach pain, upset stomach, change in colour of urine.

When should Nizonide not be used?

You should not use Nizonide tablets 500mg if you:

are allergic to nitazoxanide or any ingredients in Nizonide
are pregnant or are breastfeeding
have kidney or liver disease
are taking medicines that interact with Nizonide, including warfarin, which increases risk of drug toxicity

How should Nizonide be taken?

You should take your Nizonide tablets 500mg, swallowed whole with a glass of water and with food twice daily (every 12 hours) for 3 days. Your symptoms should improve within 3 days, if not you should visit your doctor.

How long should you take Nizonide?

You should take your Nizonide tablets 500mg for 3 days and if your symptoms have not improved you should visit your doctor.

Missed dose of Nizonide

If you miss a dose of Nizonide tablets 500mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Nizonide be stored?

You should store your Nizonide tablets 500mg below 25°C in a cool dry place.

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