Oral anti- inflammatory drugs
Oral nonsteroidal anti-inflammatory drugs (NSAID) target inflammation systemically, wherever it occurs throughout the body. They work by inhibiting the action of the enzyme cyclooxygenase (COX) that is involved in the synthesis of prostaglandins. Some NSAIDs, including celecoxib and meloxicam, are more specific and inhibit only the COX 2 enzyme that produces the inflammatory mediator prostaglandin E2, and not COX1 enzyme that is needed for normal cellular processes. These NSAIDs can be used for short-term or long-term treatment, depending on the condition, and they may help improve mobility in affected joints.
Gout uricosuric drugGout and gouty arthritis are caused by excess uric acid in the blood being deposited in joints as crystals and causing inflammation with its associated pain and swelling. Uricosuric drugs work by acting directly on the kidneys to limit the amount of uric acid in the blood and reduce crystal formation, which allows the crystals already in the joints to dissolve and the pain and swelling to be reduced.