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Cabgolin (Cabergoline 0.25mg) 4 Tablets/Pack


Cabgolin (Cabergoline 0.25mg) 4 Tablets/Pack

Cabgolin (Cabergoline 0.25mg) Tablets

 

Product Name
Cabgolin (Cabergoline 0.25mg) 4 Tablets/Pack
Also known as Dostinex
Active Ingredient
Cabergoline
Manufacturer
Sun Pharmaceuticals
Product Type
Dopamine agonist
Product expiry date we are currently shipping
Jan 2021
Product Price List
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Cabgolin (Cabergoline) 0.25mg 8 Tablets
$2.94 per Tablet
|
$23.50 (USD) 
$23.50 (USD) 
Cabgolin (Cabergoline) 0.25mg 16 Tablets
$2.41 per Tablet
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$38.50 (USD) 
$38.50 (USD) 
Cabgolin (Cabergoline) 0.25mg 28 Tablets
$2.11 per Tablet
|
$59.00 (USD) 
$59.00 (USD) 
Cabgolin (Cabergoline) 0.25mg 56 Tablets
$1.77 per Tablet
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$99.00 (USD) 
$99.00 (USD) 
Cabgolin (Cabergoline) 0.25mg 84 Tablets
$1.63 per Tablet
|
$136.50 (USD) 
$136.50 (USD) 

Cabgolin tablets 0.25mg contains cabergoline, a dopamine agonist used to treat conditions due to high prolactin levels (hyperprolactinaemia) by lowering prolactin levels; and to prevent milk production following childbirth. 

Cabgolin general information

What is Cabgolin used for?

Cabgolin tablets 0.25mg are used to treat disorders due to high levels of the hormone prolactin (hyperprolactinaemia) that can cause hormonal and menstrual disturbances in women during reproductive years including amenorrhoea (absence of periods), oligomenorrhoea (irregular periods), anovulation (when the ovaries do not release an egg during the menstrual cycle) and galactorrhoea (spontaneous release of breast milk unrelated to childbirth and breastfeeding).  Hyperprolactinaemia can also cause impotence in men and changes in breast tissue in both men and women.  Prolactin is a peptide hormone produced by the anterior pituitary gland, the lower end of the hypothalamus at the base of the brain, that plays an important role in various reproductive functions.  Abnormally high levels of prolactin can be due to a pathology like empty sella syndrome (a deformity of the pituitary gland), a prolactin secreting pituitary adenoma (tumour) or there may be no known reason (idiopathic).  The major physiological role of prolactin is to stimulate milk producing breast cells to proliferate and to induce and maintain milk production by the breast.  Cabgolin tablets 0.25mg are also used to prevent the onset of lactation following childbirth when the mother has elected not to breast feed or when breast feeding is contraindicated for the mother and the baby for medical reasons; or after a stillbirth or abortion to suppress lactation and dry up the milk supply.  

How does Cabgolin work?

Cabgolin tablets 0.25mg contain cabergoline, a dopaminergic drug belonging to the group of ergoline derivatives (structural skeleton is the alkaloid ergoline).  Prolactin secretion is under tonic inhibitory control by dopamine, a brain hormone produced by the hypothalamus.  When dopamine is released, prolactin release is inhibited, therefore, prolactin is released only when dopamine production by the hypothalamus is inhibited.  Cabergoline in Cabgolin tablets 0.25mg acts a dopamine agonist that directly stimulates dopamine receptors on the anterior pituitary cells that produce prolactin, to increase levels of dopamine and decrease prolactin levels.  This action of cabergoline in Cabgolin tablets 0.25mg provides potent, rapid and long-lasting inhibition of prolactin secretion, acting within three hours and maintaining its prolactin lowering effect for between one and four weeks.  Cabgolin tablets 0.25mg are effective in inhibiting milk secretion, as well as breast engorgement and pain after childbirth; also returning high prolactin to normal levels and relieving symptoms of hyperprolactinaemia by restoring normal menstrual cycle. 

What does Cabgolin contain?

Cabgolin tablets 0.25mg contain the active ingredient cabergoline, a dopamine agonist used to treat conditions due to high prolactin levels (hyperprolactinaemia) and to prevent milk production following childbirth. 

Treating hyperprolactinaemia with Cabgolin

Cabgolin tablets 0.25mg contain cabergoline, a dopamine agonist that is used to treat conditions due to high prolactin levels (hyperprolactinaemia).  Prolactin is a hormone produced by the anterior pituitary gland in brain that plays an important role in various reproductive functions.  Abnormally high levels of prolactin can be due to a pathology like empty sella syndrome (a deformity of the pituitary gland), a prolactin secreting pituitary adenoma (tumour) or there may be no known reason (idiopathic).  Hyperprolactinaemia can cause hormonal and menstrual disturbances in women during reproductive years including amenorrhoea (absence of periods), oligomenorrhoea (irregular periods), anovulation (when the ovaries do not release an egg during the menstrual cycle) and galactorrhoea (spontaneous release of breast milk unrelated to childbirth and breastfeeding).  Prolactin secretion is regulated by the brain hormone dopamine, produced by the hypothalamus that inhibits prolactin release.  Cabergoline in Cabgolin tablets 0.25mg acts a dopamine agonist by directly stimulating dopamine receptors on the anterior pituitary cells that produce prolactin, to increase levels of dopamine and decrease prolactin levels.  Cabgolin tablets 0.25mg are effective in returning high prolactin to normal levels and relieving symptoms of hyperprolactinaemia by restoring normal menstrual cycle. 

Cabgolin for preventing lactation

Cabgolin tablets 0.25mg contain cabergoline, a dopamine agonist that is used to either prevent lactation or dry up milk production after childbirth, still birth or an abortion.  Prolactin is a hormone produced by the anterior pituitary gland in brain and its major physiological role is to stimulate milk producing breast cells to proliferate and to induce and maintain milk production by the breast.  Prolactin secretion is regulated by the brain hormone dopamine, produced by the hypothalamus that inhibits prolactin release.  Cabergoline in Cabgolin tablets 0.25mg acts as a dopamine agonist by directly stimulating dopamine receptors on the anterior pituitary cells that produce prolactin, to increase levels of dopamine and decrease prolactin levels.  This action of Cabergoline in Cabgolin tablets 0.25mg suppresses lactation and helps dry up the milk supply, being effective rapidly and lasting for several weeks.

What are the side effects of Cabgolin?

The most commonly reported side effects when taking Cabgolin tablets 0.25mg include dizziness, fainting (syncope), vertigo, headache, nausea, vomiting, constipation, abdominal pain, heartburn, asthenia (muscle weekness), fatigue, breast pain, postural hypotension (low blood pressure when changing position), hot flushes, depression.

When should Cabgolin not be used?

You should not use Cabgolin tablets 0.25mg if you:

  • are allergic to cabergoline or any ingredients in Cabgolin
  • are pregnant, without discussion with your doctor
  • have kidney or liver disease
  • have pregnancy-induced hypertension, such as preeclampsia or post-partum hypertension, without discussion with your doctor
  • have a heart valve disorder (cardiac valvulopathy)
  • have any fibrotic disorders (scarring or thickening) of the lungs (pulmonary) around the heart (pericardial) or outside the stomach wall (retroperitoneal)
  • have severe cardiovascular disease, Raynaud's syndrome, peptic ulcer or gastrointestinal bleeding, or with a history of serious, particularly psychotic, mental disorders.
  • are taking medicines that interact with Cabgolin including ergot alkaloids used for migraine, phenothiazine, butyrophenone and thioxanthene antipsychotics, metoclopramide for reflux and nausea macrolide antibiotics like erythromycin,

What medications interact with Cabgolin?

Several medications interact with Cabgolin tablets 0.25mg and should either not be taken while you are taking Cabgolin or only after discussion and instruction from your doctor:

  • Drugs that affect Cabgolin: ergot alkaloids used for migraine, phenothiazine, butyrophenone, thioxanthene antipsychotics, metoclopramide for reflux and nausea, macrolide antibiotics like erythromycin

How should Cabgolin be taken?

You should take your Cabgolin tablets 0.25mg swallowed whole with a glass of water and with food.  For treatment of hyperprolactinaemia, you should take your Cabgolin tablets 0.25mg twice weekly and the dose you take and for how long should be as recommended by your doctor, which may be for several weeks.  For preventing lactation you should take you Cabgolin tablets 0.25mg as a single dose on the first day after delivery of your baby.

How long should you take Cabgolin?

For treatment of hyperprolactinaemia, you should continue to take your Cabgolin tablets 0.25mg for as long as recommended by your doctor, which may be for several weeks.  For preventing lactation you should take you Cabgolin tablets 0.25mg as a single dose on the first day after delivery of your baby.

Missed dose of Cabgolin

If you miss a dose of Cabgolin tablets 0.25mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Cabgolin be stored?

You should store your Cabgolin tablets 0.25mg below 25°C in a cool dry place. 

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