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Moclobemide 300mg 100 Tablets/Pack


Moclobemide 300mg 100 Tablets/Pack

Moclobemide 300mg Tablets

 

Product Name
Moclobemide 300mg 100 Tablets/Pack
Also known as Amira, Aurorix, Clobemix, Depnil or Manerix
Active Ingredient
Moclobemide
Manufacturer
Apotex
Product Type
Monoamine oxidase inhibitor (MOI)
Product expiry date we are currently shipping
Oct 2019
Product Price List
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Moclobemide 300mg 100 Tablets
$0.83 per Tablet
|
$83.00 (USD) 
$83.00 (USD) 
Moclobemide 300mg 200 Tablets
$0.76 per Tablet
|
$152.00 (USD) 
$152.00 (USD) 

Apo-Moclobemide contains moclobemide, an antidepressant of the class reversible inhibitor of monoamine oxidase A (RIMA) that is used to treat symptoms of depression and symptoms of social anxiety disorder.

Apo-Moclobemide general information

What is Apo-Moclobemide used for?

Apo-Moclobemide tablets 300mg are used to treat depression and symptoms of depressive illness, including anxiety, dysphoria (unpleasant or uncomfortable mood), loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide.  Apo-Moclobemide tablets 300mg are also used to relieve symptoms associated with social phobia or social anxiety disorder, which is the fear of social situations that involve interaction with other people, and can affect daily activities and relationships with others.  Social anxiety disorder can lead to physical symptoms including tachycardia (rapid heartbeat), gastrointestinal upset, nausea, dizziness, light-headedness and confusion. 

How does Apo-Moclobemide work?

Apo-Moclobemide tablets 300mg contain the benzamide derivative moclobemide, an antidepressant that acts as a short-acting, reversible inhibitor of monoamine oxidase A (RIMA), the enzyme that metabolises and inactivates (by a process of deamination) neurotransmitters (brain chemical that allows nerve cells to communicate) in the brain.  There are two forms of monoamine oxidase; type A and type B.  Type A monoamine oxidase preferentially inactivates monoamine neurotransmitters which include norepinephrine, dopamine and serotonin.  A chemical imbalance of brain neurotransmitters is thought to be one of the major causes of depression and other mood disorders, particularly a lack serotonin, which controls many body activities, including regulating mood.  Moclobemide in Apo-Moclobemide tablets 300mg specifically inhibits type A monoamine oxidase, thereby increasing the concentration of the monoamine neurotransmitters outside the neurones (nerve cells) of the brain and making them available for longer so that nerve cells can continue to communicate with each other to stimulate nerve pathways that control mood.  This action of moclobemide restores the balance of neurotransmitters in brain, which helps relieve symptoms of depression and social anxiety disorder.  Moclobemide in Apo-Moclobemide tablets 300mg does not have sedative properties, however, the quality of sleep associated with depression improves within days, without impairing alertness.

What does Apo-Moclobemide contain?

Apo-Moclobemide tablets contain the active ingredient moclobemide 300mg, an antidepressant used to treat depression and social anxiety disorder.  They also contain colloidal silicon dioxide, croscarmellose sodium, dextrates, magnesium stearate, carnauba wax, hypromellose, iron oxide yellow, macrogol 3350, polydextrose, titanium dioxide.

Treating depression with Apo-Moclobemide

Apo-Moclobemide tablets 300mg contain moclobemide, an antidepressant that is used to treat symptoms of depression, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating and recurrent thoughts of suicide.  Moclobemide acts directly in the brain and is a reversible inhibitor of monoamine oxidase A (RIMA), the enzyme that inactivates brain monoamine neurotransmitters (brain chemical that allows nerve cells to communicate), which include norepinephrine, dopamine and serotonin neurotransmitters.  A chemical imbalance is thought to be one of the major causes of depression and other mood disorders, particularly a lack serotonin of which controls many body activities, including regulating mood.  Moclobemide in Apo-Moclobemide tablets 300mg specifically inhibits type A monoamine oxidase, thereby increasing the amount monoamine neurotransmitters in the brain and making them available for longer to stimulate nerve pathways that control mood.  This action of moclobemide in Apo-Moclobemide tablets 300mg restores the balance of neurotransmitters in brain, which helps relieve symptoms of depression. 

Apo-Moclobemide for social anxiety disorder

Apo-Moclobemide tablets 300mg contain moclobemide, an antidepressant that is also used to treat symptoms of social anxiety disorder, which is the fear of social situations that involve interaction with other people, and can affect daily activities and relationships with others.  Symptoms of social anxiety disorder include anxiety and difficulty socialising and can lead to physical symptoms including tachycardia (rapid heartbeat).  Moclobemide in Apo-Moclobemide tablets 300mg acts directly in the brain and is a reversible inhibitor of monoamine oxidase A (RIMA), the enzyme that inactivates brain monoamine neurotransmitters (brain chemical that allows nerve cells to communicate), which include norepinephrine, dopamine and serotonin neurotransmitters.  Moclobemide specifically inhibits type A monoamine oxidase, thereby increasing the amount monoamine neurotransmitters in the brain and making them available for longer to correct the chemical imbalance that is thought to contribute to symptoms of social phobia.  

What are the side effects of Apo-Moclobemide?

The most commonly reported side effects when taking Apo-Moclobemide tablets 300mg include dry mouth, nausea, diarrhoea, constipation, vomiting, headache, insomnia, sleep disturbance, anxiety, restlessness, irritability, dizziness, visual disturbances. 

When should Apo-Moclobemide not be used?

You should not use Apo-Moclobemide tablets 300mg if you:

  • are allergic to moclobemide or any ingredients in Apo-Moclobemide
  • are pregnant or are breastfeeding, without discussion with your doctor
  • have acute confusional state
  • have phaeochromocytoma a tumor of the adrenal glands
  • are taking medicines that interact with Apo-Moclobemide, including: selegiline for for Parkinson’s disease, opiate analgesics like pethidine, cimetidine for peptic ulcers, other antidepressants, particularly the tricyclic clomipramine, the cough suppressant dextromethorphan, sympathomimetics like the decongestant and stimulant ephedrine, antihypertensives for high blood pressure

What medications interact with Apo-Moclobemide?

Several medications interact with Apo-Moclobemide tablets 300mg and should either not be taken while you are taking Apo-Moclobemide or only after discussion and instruction from your doctor:

  • Drugs that cause a serious reaction with Apo-Moclobemide: selegiline for for Parkinson’s disease, other antidepressants, particularly the tricyclic clomipramine, the cough suppressant dextromethorphan
  • Drugs that affect Apo-Moclobemide: cimetidine for peptic ulcers
  • Drugs that are affected by Apo-Moclobemide: opiate analgesics like pethidine, sympathomimetics like the decongestant and stimulant ephedrine, antihypertensives for high blood pressure

How should Apo-Moclobemide be taken?

You should take your Apo-Moclobemide tablets 300mg with a glass of water and after food, 2-3 times daily.  The dose you take depends on your condition and what you are being treated for and should be according to your doctor’s recommendations.  Your doctor may increase or decrease your dose, depending on how well you respond and any side effects.  You may not see any benefit for up to 2 weeks, but you should continue to take your Apo-Moclobemide tablets 300mg for as long as recommended by your doctor.  You should avoid tyramine-rich foods such as mature cheese, yeast extracts and fermented soya bean products while you are taking Moclobemide tablets 300mg.

How long should you take Apo-Moclobemide?

You should continue to take your Apo-Moclobemide tablets 300mg for as long as recommended by your doctor, which may be for several weeks or months, depending on your condition and your doctor’s recommendations. 

Missed dose of Apo-Moclobemide

If you miss a dose of Apo-Moclobemide tablets 300mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Apo-Moclobemide be stored?

You should store your Apo-Moclobemide tablets 300mg below 25°C in a cool dry place. 

 

All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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