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Dixarit 25mcg (Clonidine)

Dixarit general information

What is Dixarit used for?

Dixarit tablets 25mcg are used to treat several conditions in which small peripheral blood vessels are over-responsive to stimulation by chemicals that make them widen (vasodilation) or contract (vasoconstriction). These conditions include migraine headache, recurrent vascular headache and menopausal flushing. Dixarit tablets 25mcg are used to prevent changes in blood vessels in the brain associated with migraine and other vascular headaches, which helps prevent a migraine attack. They are also used to manage changes in small blood vessels in the skin which cause hot flushes, which helps relieve this common symptom associated with menopause.

How does Dixarit work?

Dixarit tablets 25mcg contain clonidine, a centrally-acting alpha-agonist (acts on the central nervous system) that stimulates alpha adrenergic receptors in the brain. This causes a negative feedback loop in the brain and inhibits the release of the neurotransmitter noradrenaline (chemical that allows nerve cells to communicate). This central inhibition of noradrenergic neurotransmission (release of noradrenaline) reduces responsiveness peripheral blood vessels in the brain to adrenergic stimuli (such as adrenaline and noradrenaline) which cause the blood vessels to widen (vasodilation) or contract (vasoconstriction). Clonidine in Dixarit tablets 25mcg reduces responsiveness of small peripheral blood vessels which can cause headaches and thereby prevents migraine attack as well as other vascular headaches. Clonidine in Dixarit tablets 25mcg also relieves menopausal flushing and it is thought to act by preventing vasodilation of peripheral blood vessels in the skin by the same mechanism, preventing increase blood flow to the skin due to dilated peripheral blood vessels, relieving hot flushes associated with loss of oestrogen during menopause.

What does Dixarit contain?

Dixarit tablets 25mcg contain the active ingredient clonidine hydrochloride, a centrally-acting alpha-agonist that is used to treat vascular headaches like migraine and menopausal hot flushes. They also contain: maize starch, colloidal anhydrous silica, povidone, stearic acid, starch, calcium hydrogen phosphate, and lactose.

Treating migraine headache with Dixarit

Dixarit tablets 25mcg contain clonidine, a centrally-acting alpha-agonist that interacts directly with alpha adrenergic receptors in the brain, which inhibits the release of the neurotransmitter noradrenaline (chemical that allows nerve cells to communicate). Migraine headaches are thought to happen when blood vessels in the brain contract and expand inappropriately. Stimulation of alpha adrenergic receptors by clonidine in Dixarit tablets 25mcg reduces the responsiveness of small blood vessels in the brain to adrenergic stimuli (such as noradrenaline) which causes blood vessels to widen (vasodilation) or contract (vasoconstriction). Dixarit 25mcg is used to prevent changes in blood vessels in the brain associated with migraine and other vascular headaches, which helps prevent a migraine attack.

Dixarit for relieving menopausal hot flushes

Dixarit tablets 25mcg contain clonidine, a centrally-acting alpha-agonist that interacts directly with alpha adrenergic receptors in the brain, which inhibits the release of the neurotransmitter (chemical that allows nerve cells to communicate). During menopause levels of oestrogen fall and this causes a variety of hormonal-related menopausal symptoms, including disruption in regulation of body temperature leading to hot flashes, when peripheral blood vessels in the skin become dilated increasing blood flow to the skin. Stimulation of alpha adrenergic receptors by clonidine in Dixarit tablets 25mcg reduces the responsiveness of small blood vessels and helps prevent changes in small blood vessels in the skin, relieving symptoms of hot flushes.

What are the side effects of Dixarit?

The most commonly reported side effects when taking Dixarit include: sleep disturbances, depression, dizziness, sedation, fatigue, headache, confusion, nausea, vomiting, orthostatic hypotension, constipation, dry mouth, nausea, salivary gland pain, vomiting, sexual problems.

When should Dixarit not be used?

You should not use Dixarit tablets 25mcg if you:
  • are allergic to clonidine or any ingredients in Dixarit
  • are pregnant (without discussion with your doctor) or are breastfeeding
  • have very slow, severe bradyarrhythmias (abnormal heart rhythms)
  • have kidney disease
  • are taking medicines that interact with Dixarit, including: beta-receptor blockers, digoxin, phentolamine for hypertensive emergencies; tolazoline used to treat spasms of peripheral blood vessels; alcohol, tricyclic anti-depressants, diuretics, vasodilators, beta-receptor blockers, calcium antagonists, ACE-inhibitors

What medications interact with Dixarit?

Several medications interact with Dixarit tablets 25mcg and should either not be taken while you are taking Dixarit or only after discussion and instruction from your doctor:
  • Drugs that cause a serious reaction with Dixarit: beta-receptor blockers, digoxin
  • Drugs that affect Dixarit: phentolamine for hypertensive emergencies; tolazoline used to treat spasms of peripheral blood vessels; alcohol, tricyclic anti-depressants
  • Drugs that are affected by Dixarit: diuretics, vasodilators, beta-receptor blockers, calcium antagonists, ACE-inhibitors

How should Dixarit be taken?

You should take your Dixarit tablets 25mcg with a glass of water with or without food, twice daily. The dose you take depends on your condition and your doctor’s recommendations. If required, your doctor may increase your dose. It may take 2-4 weeks until Dixarit is fully effective and you should continue to take your Dixarit tablets 25mcg daily for as long as recommended by your doctor.

How long should you take Dixarit?

It may take 2-4 weeks until Dixarit tablets 25mcg are fully effective and you should continue to take your Dixarit tablets 25mcg daily for as long as recommended by your doctor.

Missed dose of Dixarit

If you miss a dose of Dixarit tablets 25mcg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Dixarit be stored?

You should store your Dixarit below 25°C in a cool dry place.



Boehringer IngelheimAlpha-agonist
From $0.23 per DoseGBPInhouseChemist.vuNewOut of Stock1Dixarit 25mcg 100 Tablets/Pack
Dixarit 25mcg (Clonidine)


Dixarit 25mcg (Clonidine)

Dixarit 25mcg (Clonidine)

.

Product Name
Dixarit 25mcg 100 Tablets/Pack
Active Ingredient
Clonidine
Manufacturer
Boehringer Ingelheim
Product Type
Alpha-agonist
Product expiry date we are currently shipping
Discontinued, no stock
Product Price List
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This product has been discontinued, but we do have alternatives below.

Dixarit contains clonidine, a centrally-acting alpha-agonist that is used to treat vascular headaches like migraine and menopausal hot flushes.

Dixarit general information

What is Dixarit used for?

Dixarit tablets 25mcg are used to treat several conditions in which small peripheral blood vessels are over-responsive to stimulation by chemicals that make them widen (vasodilation) or contract (vasoconstriction). These conditions include migraine headache, recurrent vascular headache and menopausal flushing. Dixarit tablets 25mcg are used to prevent changes in blood vessels in the brain associated with migraine and other vascular headaches, which helps prevent a migraine attack. They are also used to manage changes in small blood vessels in the skin which cause hot flushes, which helps relieve this common symptom associated with menopause.

How does Dixarit work?

Dixarit tablets 25mcg contain clonidine, a centrally-acting alpha-agonist (acts on the central nervous system) that stimulates alpha adrenergic receptors in the brain. This causes a negative feedback loop in the brain and inhibits the release of the neurotransmitter noradrenaline (chemical that allows nerve cells to communicate). This central inhibition of noradrenergic neurotransmission (release of noradrenaline) reduces responsiveness peripheral blood vessels in the brain to adrenergic stimuli (such as adrenaline and noradrenaline) which cause the blood vessels to widen (vasodilation) or contract (vasoconstriction). Clonidine in Dixarit tablets 25mcg reduces responsiveness of small peripheral blood vessels which can cause headaches and thereby prevents migraine attack as well as other vascular headaches. Clonidine in Dixarit tablets 25mcg also relieves menopausal flushing and it is thought to act by preventing vasodilation of peripheral blood vessels in the skin by the same mechanism, preventing increase blood flow to the skin due to dilated peripheral blood vessels, relieving hot flushes associated with loss of oestrogen during menopause.

What does Dixarit contain?

Dixarit tablets 25mcg contain the active ingredient clonidine hydrochloride, a centrally-acting alpha-agonist that is used to treat vascular headaches like migraine and menopausal hot flushes. They also contain: maize starch, colloidal anhydrous silica, povidone, stearic acid, starch, calcium hydrogen phosphate, and lactose.

Treating migraine headache with Dixarit

Dixarit tablets 25mcg contain clonidine, a centrally-acting alpha-agonist that interacts directly with alpha adrenergic receptors in the brain, which inhibits the release of the neurotransmitter noradrenaline (chemical that allows nerve cells to communicate). Migraine headaches are thought to happen when blood vessels in the brain contract and expand inappropriately. Stimulation of alpha adrenergic receptors by clonidine in Dixarit tablets 25mcg reduces the responsiveness of small blood vessels in the brain to adrenergic stimuli (such as noradrenaline) which causes blood vessels to widen (vasodilation) or contract (vasoconstriction). Dixarit 25mcg is used to prevent changes in blood vessels in the brain associated with migraine and other vascular headaches, which helps prevent a migraine attack.

Dixarit for relieving menopausal hot flushes

Dixarit tablets 25mcg contain clonidine, a centrally-acting alpha-agonist that interacts directly with alpha adrenergic receptors in the brain, which inhibits the release of the neurotransmitter (chemical that allows nerve cells to communicate). During menopause levels of oestrogen fall and this causes a variety of hormonal-related menopausal symptoms, including disruption in regulation of body temperature leading to hot flashes, when peripheral blood vessels in the skin become dilated increasing blood flow to the skin. Stimulation of alpha adrenergic receptors by clonidine in Dixarit tablets 25mcg reduces the responsiveness of small blood vessels and helps prevent changes in small blood vessels in the skin, relieving symptoms of hot flushes.

What are the side effects of Dixarit?

The most commonly reported side effects when taking Dixarit include: sleep disturbances, depression, dizziness, sedation, fatigue, headache, confusion, nausea, vomiting, orthostatic hypotension, constipation, dry mouth, nausea, salivary gland pain, vomiting, sexual problems.

When should Dixarit not be used?

You should not use Dixarit tablets 25mcg if you:
  • are allergic to clonidine or any ingredients in Dixarit
  • are pregnant (without discussion with your doctor) or are breastfeeding
  • have very slow, severe bradyarrhythmias (abnormal heart rhythms)
  • have kidney disease
  • are taking medicines that interact with Dixarit, including: beta-receptor blockers, digoxin, phentolamine for hypertensive emergencies; tolazoline used to treat spasms of peripheral blood vessels; alcohol, tricyclic anti-depressants, diuretics, vasodilators, beta-receptor blockers, calcium antagonists, ACE-inhibitors

What medications interact with Dixarit?

Several medications interact with Dixarit tablets 25mcg and should either not be taken while you are taking Dixarit or only after discussion and instruction from your doctor:
  • Drugs that cause a serious reaction with Dixarit: beta-receptor blockers, digoxin
  • Drugs that affect Dixarit: phentolamine for hypertensive emergencies; tolazoline used to treat spasms of peripheral blood vessels; alcohol, tricyclic anti-depressants
  • Drugs that are affected by Dixarit: diuretics, vasodilators, beta-receptor blockers, calcium antagonists, ACE-inhibitors

How should Dixarit be taken?

You should take your Dixarit tablets 25mcg with a glass of water with or without food, twice daily. The dose you take depends on your condition and your doctor’s recommendations. If required, your doctor may increase your dose. It may take 2-4 weeks until Dixarit is fully effective and you should continue to take your Dixarit tablets 25mcg daily for as long as recommended by your doctor.

How long should you take Dixarit?

It may take 2-4 weeks until Dixarit tablets 25mcg are fully effective and you should continue to take your Dixarit tablets 25mcg daily for as long as recommended by your doctor.

Missed dose of Dixarit

If you miss a dose of Dixarit tablets 25mcg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Dixarit be stored?

You should store your Dixarit below 25°C in a cool dry place.



All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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