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Dexamethasone 1mg 100 Tablets/Pack


Dexamethasone 1mg 100 Tablets/Pack

Dexamethasone 1mg Tablets

 

Product Name
Dexamethasone 1mg 100 Tablets/Pack
Active Ingredient
Dexamethasone 1mg
Manufacturer
Douglas Pharmaceuticals
Product Type
Corticosteroid, anti-inflammatory
Product expiry date we are currently shipping
Discontinued, no stock

This product has been discontinued, but we do have alternatives below.

Other Strengths


Dexamethasone tablets 1mg contain dexamethasone, a potent anti-inflammatory corticosteroid used to treat a wide range of inflammatory, allergic and immune disorders.   

Dexamethasone general information

What is Dexamethasone used for?

Dexamethasone tablets 1mg are a steroid medication used in wide range of inflammatory, allergic and immune disorders to suppress clinical symptoms of the disease.  Amongst their many applications, Dexamethasone tablets 1mg are used to reduce inflammation in conditions where the immune system is overactive, like anaphylaxis, severe bronchial asthma, acute outbreaks of eczema and severe allergies; to reduce inflammation and suppress the immune system in autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus, ulcerative colitis, or Crohn's disease, where the body’s immune system is directed against self, and to prevent rejection following organ transplant.  Also to treat skin conditions like pemphigus, secondary hypercalcaemia, autoimmune haemolytic anaemias, oedema and some eye disorders.  Dexamethasone tablets 1mg are also used as an anti-cancer medication along with other drugs, to treat certain tumours like leukemia and lymphoma.  Brain tumours can cause swelling of the brain and Dexamethasone tablets 1mg can be used to counteract the development of oedema.  Dexamethasone tablets 1mg are used as replacement therapy in secondary adrenal insufficiency, due to insufficient production of the hormone corticotrophin by the pituitary gland, resulting in lack of the natural corticosteroid cortisol by the adrenal glands, which can affect the ability of the body to regulate blood pressure, blood sugar, energy levels, normal development and protect against stress.  Dexamethasone tablets 1mg should not be used for primary adrenal insufficiency, such as Addison’s disease or after removal of the adrenal gland as other adrenal hormones are also deficient in these conditions and cannot be replaced by dexamethasone.   

How does Dexamethasone work?

Dexamethasone tablets 1mg contain dexamethasone, a potent synthetic corticosteroid hormone (glucocorticoid) with up to 7 times greater anti-inflammatory potency than prednisolone a synthetic derivative of the natural glucocorticoid cortisol, and 25 times greater potency than hydrocortisone, a naturally occurring glucocorticoid corticosteroid.  Dexamethasone also has anti-allergic, antipyretic and immunosuppressive properties but has very little water or salt retaining properties (mineralocorticoid) properties and is longer lasting than other synthetic corticosteroids.  Dexamethasone acts directly through the glucocorticoid receptor that is expressed inside most cells of the body and regulates transcription of specific genes that control many aspects of development, metabolism and the immune response, and this results in widespread effects acting on most tissues in the body to modify, glucose, fat, protein and calcium metabolism.  The major therapeutic actions of dexamethasone are to reduce the vascular (blood vessels) and cellular inflammatory response primarily by blocking the production of inflammatory cytokines, like prostaglandins and leukotrienes, from inflammatory cells to reduce the swelling, redness and pain associated with inflammation; to modify the actions of cells involved in the allergic response, and to suppress the immune system to prevent rejection following organ transplant.  Dexamethasone also has anti-cancer properties and has been found to inhibit cell growth of certain tumours. 

What does Dexamethasone contain?

Dexamethasone tablets contains the active ingredient dexamethasone tablets 1mg.  They also contain magnesium stearate, talc, lactose, maize cornflour, polyvinylpyrrolidinone, and sodium starch glycolate.

Treating inflammation with Dexamethasone

Dexamethasone tablets 1mg contain dexamethasone, a potent synthetic corticosteroid hormone that is used to treat a wide range of inflammatory, allergic and immune disorders to suppress clinical symptoms of the disease due to inflammation.  These conditions include severe bronchial asthma, acute outbreaks of eczema and severe allergies; autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus, ulcerative colitis, or Crohn's disease, where the body’s immune system is directed against self.  Dexamethasone tablets 1mg are also used to help control oedema, which often accompanies brain tumours, to reduce swelling.  Dexamethasone acts directly through the glucocorticoid receptor that is expressed inside most cells of the body and regulates transcription of specific genes that control many aspects of development, metabolism and the immune response, and this results in widespread effects acting on most tissues in the body to modify, glucose, fat, protein and calcium metabolism.  The major therapeutic actions of dexamethasone are to reduce the vascular (blood vessels) and cellular inflammatory response primarily by blocking the production of inflammatory cytokines, like prostaglandins and leukotrienes, from inflammatory cells to reduce the swelling, redness and pain associated with inflammation.

Dexamethasone for adrenal hormone replacement therapy

Dexamethasone tablets 1mg contain dexamethasone that is used as replacement therapy for the adrenal hormone cortisol in secondary adrenal insufficiency, which is due to insufficient production of the hormone corticotrophin by the pituitary gland, resulting in lack of the natural corticosteroid cortisol by the adrenal glands.  A lack of cortisol can affect the ability of the body to regulate blood pressure, blood sugar, energy levels, normal development and protect against stress.  It should not be used for primary adrenal insufficiency, such as Addison’s disease or after removal of the adrenal gland, as other adrenal hormones are also deficient and cannot be replace by dexamethasone alone, which is a glucocorticoid hormone and has very little water or salt retaining properties (mineralocorticoid) required to replace hormones controlling salt and water balance (aldosterone).

What are the side effects of Dexamethasone?

The most commonly reported side effects when taking Dexamethasone tablets 1mg include, increased susceptibility to infection, muscle or bone aches and pains, weight gain, thinning of skin, bone demineralisation, slow wound healing, acne, redistribution of body fat creating the typical moon face, altered vision. Also behavioural and mood disturbances such as depression, irritability, anxiety, sleep disturbances.

When should Dexamethasone not be used?

You should not use Dexamethasone tablets 1mg if you:

  • are allergic to dexamethasone or any ingredients in Dexamethasone tablets
  • are pregnant or are breastfeeding
  • have kidney or liver disease
  • have hypothyroidism, high blood pressure, congestive heart failure or recent myocardial infarction
  • have mood disorders, psychosis, epilepsy, diabetes, glaucoma, osteoporosis, migraine, peptic ulcers
  • have any infectious disease, acute infection, systemic fungal infection, tuberculosis, uncomplicated viral hepatitis
  • are due to receive a vaccination with a live virus vaccine
  • are taking medicines that interact with Dexamethasone, including rifampicin for serious bacterial infections like tuberculosis, barbiturates, the anticonvulsants phenytoin, primidone and carbamazepine, aminoglutethimide for breast cancer, antidiabetic drugs including insulin, the antifungal ketoconazole, anti-inflammatories like diclofenac, ibuprofen and aspirin, diuretics and digoxin for heart failure, coumarin anticoagulants like warfarin, oral contraceptives, antacids for reflux

What medications interact with Dexamethasone?

Several medications interact with Dexamethasone and should either not be taken while you are taking Dexamethasone or only after discussion and instruction from your doctor:

  • Drugs that cause a serious reaction with Dexamethasone: anti-inflammatories like diclofenac and ibuprofen, diuretics and digoxin for heart failure
  • Drugs that affect Dexamethasone: rifampicin for serious bacterial infections like tuberculosis, barbiturates, the anticonvulsants phenytoin, primidone and carbamazepine, aminoglutethimide for breast cancer, the antifungal ketoconazole, coumarin anticoagulants like warfarin, oral contraceptives, antacids for reflux
  • Drugs that are affected by Dexamethasone: antidiabetic drugs including insulin, live virus vaccine may be less effective

How should Dexamethasone be taken?

You should take your Dexamethasone tablets 1mg swallowed whole with a glass of water and with food.  The dose that you take, how often and for how long depends on what you are being treated for and as recommended by your doctor.  You should continue to take your Dexamethasone tablets 1mg for as long as recommended by your doctor and should not stop taking them suddenly; withdrawal should be gradual to reduce risk of side effects.   

How long should you take Dexamethasone?

You should continue to take your Dexamethasone tablets 1mg for as long as recommended by your doctor and should not stop taking them suddenly; withdrawal should be gradual to reduce risk of side effects.   

Missed dose of Dexamethasone

If you miss a dose of Dexamethasone tablets 1mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Dexamethasone be stored?

You should store your Dexamethasone tablets 1mg below 25°C in a cool dry place. 

 

All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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